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Search Results - pathogenic (variable OR valuables)
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Skin Microbiome Dynamics and Strain-Level Dysbiosis in Acne Vulgaris: Evidence from Diverse Egyptian Populations
Published 2026“…Recent findings highlight the importance of the skin microbiome, in particular the diversity and strain variability of Cutibacterium acnes, in the pathogenesis of acne. …”
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Optimisation of a flow cytometry antibody panel to detect BCG-induced innate responses in infants
Published 2024“…The underlying basis of the variable disease outcomes to mycobacterial exposure is largely unknown and is thought to involve a complex interplay between genetic variation in both host and pathogen. …”
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Computational analysis of the immunogenicity and sequence diversity of Mycobacterium tuberculosis PPE_MPTR proteins
Published 2017Get full text
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Hyperphosphatasia with mental retardation syndrome in South Africa: identifying a recurring PGAP3 variant
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Evolution of phyllospheric microorganisms on Vitis vinifera L. cvs. Pinot noir and Chardonnay
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Phylogenetic characterisation of the Palyam serogroup orbiviruses and development of a real-time RT-PCR
Published 2019Get full text
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The psychological impact of rape : a long longitudinal study of adult female survivors in the Western Cape, South Africa
Published 2014Get full text
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SEASON OF HARVEST OF AMARANTHUS CRUENTUS L. IN RELATION TO SEED-BORNE MYCOFLORA AND MAJOR SHOOT DISEASES
Published 1990-04ThesisFull Text AvailableAccess Repository -
CRISPRI-based high-throughput functional genomic approaches for use in mycobacteria
Published 2022“…Taken individually, or in combination, these methodologies can be utilised to increase fundamental understanding of mycobacteria, including the pathogenic M. tuberculosis…”
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Kaposi's sarcoma: Genetic subtypes and clinical correlation in a South African population
Published 2017“…Seven major subtypes (A, B, C, D, E, F, Z) based on genetic variability of open reading frame (ORF)-K1, have been identified. …”
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Barriers to tuberculosis drug discovery: the mycobacterial cell wall
Published 2023“…This presents a potentially novel form of intrinsic resistance whereby stripping of the cell wall could allow for tolerance to cell wall active antibiotics, a previously under-appreciated strategy that has been reported in other pathogenic bacteria. Together, these findings highlight the highly dynamic nature of the mycobacterial cell envelope and the need for further investigation into the properties of this structure that allow for such efficient antibiotic evasion.…”
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Development of a bioprocess for the production of an aquaculture biological agent
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Perspectives and Experiences of Individuals Undergoing Predictive Testing for Hereditary Breast and Ovarian Cancer (HBOC) Syndrome in the Western Cape, South Africa.
Published 2019“…Hereditary breast and ovarian cancer (HBOC) syndrome is caused by pathogenic variants in BRCA1 and BRCA2 and is seen in approximately 50% of families with a strong history of breast and ovarian cancers. …”
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Genealogical tracing of founder variants linked to cardiomyopathies in a South African cohort
Published 2025“…The IMHOTEP registry was established to clinically and genetically characterise affected patients and through this study several common pathogenic variants were identified, suggesting potential founder variants. …”
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Selection of bacterial species from wastewater for potential production of poly (γ-glutamic acid): isolation, characterisation and growth kinetics
Published 2022“…This includes the recovery or the production of valuable resources, whilst in turn recovering clean water. …”
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Pilot study into the molecular mechanisms of canine distemper virus infection
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