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Pharmacogenomics of sickle cell disease therapeutics: pain and drug metabolism associated gene variants and hydroxyurea-induced post-transcriptional expression of miRNAs
Published 2022“…This project aimed to investigate the clinical and genetic predictors of painful vaso-occlusive crisis (VOC) among SCD Cameroon patients by exploring pharmacokinetic determinants of treatment responses as well as post-transcriptional signatures triggered by hydroxyurea treatment, particularly, miRNA expression. …”
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Mode of action studies of defensin peptides from native South African Brassicaceae species
Published 2013Get full text
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Reading Ruth allegorically : an intertextual, and Canonical analysis
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Auditory and non-auditory effects of consistent-use of mobile- telephone in Ibadan-Oyo State, Nigeria
Published 2020-05ArticleFull Text AvailableAccess Repository -
Widening readership – a case study of the translation of indigenous law
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Where infrastructure alone is not enough: developing well-functioning non-motorized transport with a focus on cycling in the 'Northern-Inner' district of Cape Town
Published 2017“…Post-apartheid Cape Town is characterized largely by a sprawling and inequitable city form. …”
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Functional Genome-wide Association Studies (fGWAS) and genomics landscape of signatures of polygenic adaptation in Botswana populations with HIV-1 C infection
Published 2023“…Alternatively, functional genome-wide association studies (fGWAS), which are post-GWAS analyses, can be utilized to put GWAS summary results into functional context. …”
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Exploring the processes of parenting in the context of multidimensional poverty when children demonstrate behavioural problems: a single case study in post-1994 Apartheid South Afr...
Published 2025“…Methodology: Drawing upon a post-structuralist paradigm, the study adopted a qualitative single, intrinsic case study design. …”
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A patient-specific adaptation of the Living Human Heart Model in application to pulmonary hypertension
Published 2020“…Comparison of patient geometry pre-operation and post-surgery showed a change in shape of the Tricuspid Annulus (TA) in systole. …”
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Determinants of positive functional outcomes at 16 weeks after flexor tendon repair at a teritiary hospital in South Africa. A descriptive, analytical study
Published 2020“…The objectives were: 1) to describe the functional outcomes at four, eight, twelve and sixteen weeks post flexor tendon repair using total active motion (TAM), muscle strength and the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire, 2) to ascertain the demographic profile for patients presenting to the hospital with a flexor tendon injury, 3) to describe the rate of recovery between the four assessment intervals, and 4) to cross-culturally translate the DASH questionnaire into isiXhosa. …”
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