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Investigation of minor groove binders (MGB), non-ionic surfactant vesicles (NIV) delivery systems and IL-4i1 as novel pathogen- and host-directed drug therapy for tuberculosis
Published 2020“…We identified host target genes that may play a role in host immune subverting mechanism by Mtb to hide away from host effector functions providing a possible target for host-directed therapy for tuberculosis. …”
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Investigation of molecular regulatory control of the cardiac-enrich acetyl-CoA carboxlase
Published 2024“…ACCa and ACC~ were analagously regulated in response to hypoxia and hypoxia-induced hypertrophy indicating that these isoforms have similar regulatory functions. A novel 764 bp fragment in 5'-flanking region of the rat ACC~ gene which may play a role in the transcription and/or post-transcriptional regulation of this gene in response to nutritional flux was isolated and characterised.…”
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Analysis of driver gene mutations in oesophageal squamous cell carcinoma
Published 2026“…These mutations cause significant structural alterations that disrupt interactions crucial for p16INK4a stability and function, possibly affecting cell cycle regulation and potentially promoting tumorigenesis in OSCC. …”
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Hydrogels based on poly(styrene-co-maleic anhydride) for the application of reversible male contraceptive
Published 2016Get full text
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Trauma Counselling: Perceptions of Clients at the Trauma Centre for the Survivors of Violence and Torture
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XvERD15, an early-responsive gene to stress from Xerophyte viscosa
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Immune cell dysfunction and eicosanoid imbalance in chronic diabetic wounds
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The implementation of the national HIV/AIDS policy in the Vhembe District
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The challenges of border issues, documentation, and infrastructure in intra-African trade
Published 2020“…In 21st century post-colonial Africa, African leaders have visualised, mobilised, and worked towards economic advancement nationally, regionally, and continentally. …”
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The development and assessment of the mayoral dashboard performance monitoring system in the City of Cape Town
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A randomised control trial comparing occupational therapy interventions that aim to improve developmental outcomes for HIV9positive children (aged 6 months - 5 years) on ART
Published 2017“…Twenty-eight participants completed mid and post assessments, 15 in the experimental PICIHBI group and 13 in the control group (90% power). …”
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An analysis of the status of orchestras in South Africa
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