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In silico design of selective high affinity ligands against HCV using novel computational diology tools
Published 2011“…In addition, blocking the complexation of NS3 with the NS4A co-factor will render it non functional and thus block the replication process and disrupt the HCV life cycle. If a reliable E2 homology model was developed based on different studies and validations, it could help generate selective high affinity ligands that block the earliest phase of the HCV life cycle.…”
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End-of-life in South African product life cycle assessment
Published 2019“…This result implies that if landfill disposal is modelled over the long-term, the potential impacts of the process has less to do with site-specific conditions than it does to do with the intrinsic properties of the material itself. …”
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Longitudinal vehicle dynamics control for improved vehicle safety
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Strategic thinking by non-government organisations for sustainability : a review of the logical framework approach
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Validation of numerical prediction of bone ingrowth into cementless implants
Published 2018“…Nevertheless, the finite element method was assessed as being a tool with great potential, and modifications to the present model may provide more reliable results. A time study was also undertaken, whereby the tissue density was evaluated at various periods after the operation. …”
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Experimental Insights into Friction Losses of Post-Tensioned Precast Full-Scale Girders
Published 2024“…Through this on-site investigation, the thesis provides empirical evidence highlighting that the friction losses occurring during the tensioning process are more pronounced and develop more rapidly than conventional models and standards predict. …”
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The brain age gap in social anxiety disorder
Published 2022“…This should be verified in future research by using multiple different machine learning models based on different feature sets, to obtain more reliable and robust brain age estimates.…”
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Predicting stage performance of a multi-stage centrifugal compressor using the overall compressor performance characteristic
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The feasibility of implementing online dispute resolution as a distinct method of dispute resolution on the African continent
Published 2025“…Online Dispute Resolution (ODR) has been identified as such a system, a dispute resolution process which is in large part conducted through online systems or through the use of technology. …”
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The Removal of False Signals from Convolutional Neural Networks
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The evaluation of polarization parameters as quality predictors for zinc electroplated from acidic sulphate solutions
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Finding Neverland? Artificial Intelligence and the Jurisprudence of Legal Certainty
Published 2021“…I further argue that, inversed-AI models possess inherent inadequacies and, consequently, are at fundamental odds with the decision-making process; thus, preventing them from being reliable indicators of AI’s potential in the legal process. …”
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A managerial decision support tool for the use of cryptocurrency mining to hedge renewable energy investments
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Robust time spectral methods for solving fractional differential equations in finance
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Differences in the quality of school-based assessment : evidence for Grade 9 Mathematics achievement
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The influence of leader behaviour, psychological empowerment, job satisfaction, and organizational commitment on turnover intention
Published 2011Get full text
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