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Genetic and pharmacokinetics factors associated with susceptibility to kanamycin induced cochleotoxicity in a cohort of patients undergoing MDR/RR-TB treatment
Published 2023“…However, not much is known about the pharmacokinetics of Kanamycin and there is currently limited research available on the role of mutations involved in aminoglycoside-induced cochleotoxicity in South Africa. Therefore, this study aimed to determine: (1) the incidence of cochleotoxicity in MDR/RR-TB patients who are receiving kanamycin, (2) the pharmacokinetic properties of kanamycin that are associated with increased risk of cochleotoxicity, and (3) the association between participant's susceptibility to develop cochleotoxicity and two potentially pathogenic mitochondrial mutations (T15312C (I189T in MT-CYB) and T10114C (I19T in MT-ND3)). …”
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An assessment of the performance appraisal process in Pelonomi Tertiary Hospital
Published 2016Get full text
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Characterization of and risk factors for HIV-1 resistance mutations following first line antiretroviral failure in the southern African private sector
Published 2017“…Background: First-line antiretroviral therapy (ART) regimen choices have evolved over the past 15 years in South Africa. Many patients develop HIV drug resistance mutations when they fail first-line ART. …”
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Genetic analysis of bipolar disorder and alcohol use disorder
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A study on dormancy and chilling requirement of peaches and nectarines
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Eskom's employees perception on nuclear power in accordance with the IRP 2010 Nuclear Energy Plan
Published 2018“…The Republic of South Africa's (RSA) progress towards its largest nuclear procurement program is taking place in the midst of changes within the African National Congress (ANC) ruling party, an increase in global demand for uranium and growing energy needs within South Africa. …”
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n Standaardstelling en metingskriteria vir arbeidsterapie-werkbepalingsareas
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A comparative analysis of the Employment Tax Incentive Act, no.26 of 2013
Published 2016“…The following extract is from the Explanatory Memorandum on the Employment Tax Incentive Bill, 2013: "High youth unemployment means young people are not gaining the skills or experience needed to drive the economy forward. (…) In response to the high rate of youth unemployment, government wishes to implement an incentive mainly aimed at encouraging employers to hire young and less experienced work seekers, as stated in the National Development Plan. The incentive is one among many that will fall under the umbrella of government's youth employment strategy, the National Youth Accord, which outlines a program of action to address youth unemployment." …”
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Effects of demersal trawling on marine infaunal, epifaunal and fish assemblages: studies in the southern Benguela and Oslofjord
Published 2014“…Biological traits analysis of benthic invertebrates shows promise as a practical technique for incorporation into monitoring programmes and for developing indicators of benthic ecosystem health, needed for implementation of an ecosystem approach to fisheries management in South Africa. …”
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An integrated linkage map of perlemoen (haliotis midae)
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Investigation of wind patterns on Marion Island using Computational Fluid Dynamics and measured data
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Evaluation of Burnout, Coping Strategies and Resilience in Paediatric Oncology Health Care Workers in Cape Town
Published 2019“…Research into the phenomenon of burnout and associated factors in POU HCWs is low in South Africa in spite of the global attention it has commanded. …”
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Pressure-based leakage characterisation of bulk pipelines
Published 2020“…Water losses in distribution systems are a huge problem internationally and also in South Africa where more than a third of the water entering the water supply networks is lost through pipe leaks. …”
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Acaricidal efficacy of crude extracts and isolated flavonoids from Calpurnia aurea subsp. aurea against Rhipicephalus turanicus
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