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Investigation of particulate Bluetongue virus vaccines made in plants
Published 2023“…Although a number of different BTV VLPs have been produced in traditional protein expression systems, such as insect cells, these production methods are considered too expensive to compete with those of the commercial vaccines. …”
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A proteomic approach to investigate the response of tef (Eragrostis tef) to drought
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Immunogenic assessment of plant-produced Human papillomavirus type 16 chimaeric L1:L2 virus-like particles and the production of an encapsidated therapeutic DNA vaccine candidate
Published 2018“…However, these vaccines are produced in expensive cell culture systems, are type-specific and do not induce the regression of established infections. …”
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The Development of an African Horse Sickness Virus VP7 Quasi-Crystal Vaccine Candidate in N. benthamiana
Published 2020“…TNFSF14 and CX3CR1 play a role in T-cell proliferation and cytotoxic T-cell responses respectively. …”
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Development of plant-produced African horse sickness vaccines
Published 2021“…Co-infiltration of Nicotiana benthamiana plants with Agrobacterium constructs encoding the four AHSV serotype 5 structural proteins VP2, VP3, VP5 and VP7, was shown to result in assembly of complete VLPs. …”
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The amino acid sequence of chicken histone F3
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Midaesin - a histone H2A antimicrobial peptide from the South African abalone, Haliotis midae
Published 2022“…Secondary structure analysis by circular dichroism indicated a shift in the secondary structure of the Midaesin-containing peptide upon incubation with V. anguillarum cells for 30 minutes with a trend towards more α-helical content. …”
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Protein purification and cDNA cloning of suGF1 : a sea urchin nuclear DNA-binding factor
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Skeletal element elongation and interdigital tissue regression in developing bat limbs: a gene expression analysis
Published 2016“…Meis2 is suggested to play a role in interdigital tissue retention, enhancing cell proliferation and contributing to wing expansion. 5'HoxD genes (Hoxd10 - 13) are involved in limb patterning, digit formation and growth. …”
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Studies on the regulation of nitrogen metabolism in clostridium acetobutylicum NCP 262 and clostridium beijerinckii NCIMB 8052
Published 2024“…Leaders of three of the transcripts were found to be capable of forming identical terminator structures upstream of the start codon of ginA, however potential antiterminator structures differed for each transcript. …”
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The investiation into the synthesis of 2,5-Diphenyloxazole in Streptomyces polyantibioticus SPR
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Identification and preliminary characterization of the 2,5-diphenyloxazole biosynthetic pathway in streptomyces polyantibioticus SPRT
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Rat liver nuclear envelope insulin binding and its effects on endogenous protein kinases
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Regulation of transcription in Plasmodium falciparum, the causative agent of severe malaria: initial characterisation of PfTBP and PfTFIIA
Published 2018“…The severity of the disease is brought about by the variable expression of parasite proteins on the surface of infected red blood cells. The substantial morphological changes, together with the variable expression of cell surface proteins, are governed by tightly controlled stage-specific changes in gene expression patterns. …”
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The impact of HIV-1 subtype C Envelope N-glycosylation on DC-SIGN meditated modulation of DC function to facilitate transmission or enhance viral pathogenesis
Published 2018“…In this study, we hypothesized that Env N-glycosylation may affect viral pathogenesis by influencing Env structure and function. Furthermore, we also postulated that differences in Env glycosylation could affect interactions between Env and DC-SIGN of dendritic cells (DCs), activating alternative signalling pathways which stimulate the release of different immune modulators. …”
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Development of a plant-made immunoassay for the detection of Porcine circovirus infections in South African swine herds
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Functional Characterization of Plasmodium falciparum TATA-box binding-like Protein (PfTLP)
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Expression optimization of a human papillomavirus type 16 therapeutic vaccine candidate in Nicotiana benthamiana leaves
Published 2017“…Plant expression systems represent an attractive alternative to conventional expression systems based on bacterial, yeast, mammalian and other cell cultures, and are potentially far more cost- effective. …”
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