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The analysis of genetic aberrations in South African oesophageal squamous cell carcinoma patients
Published 2023“…Estimates for 2017 indicate that 20% of cancers globally are gastrointestinal tract (GIT) cancers, with oesophageal cancer being the 8th most common cancer. Oesophageal squamous cell carcinoma (OSCC) occurs in the upper to mid oesophagus and is present at high incidence in developing countries including South Africa. …”
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The influence of immobilisation and peptide structure on the bioactivity of model antimicrobial peptides
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Preparation and characterisation of inorganic nanostructured support materials for polymer electrolyte fuel cells
Published 2016“…Polymer electrolyte fuel cells (PEFCs) have been identified as a safe, clean and reliable alternative energy conversion technology to conventional, fossil fuel based, ones. …”
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Hydrolysis of cassava cell walls through alkaline treatment and fermentation with alkaliphilic bacteria
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Knowledge and experiences of parents with children affected by Sickle Cell Disease in Cape Town
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Preparation and characterisation of Pt-Ru/C catalysts for direct methanol fuel cells
Published 2017“…The direct methanol fuel cell (DMFC) is identified as a promising fuel cell for portable and micro fuel cell applications. …”
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Synthesis and mechanistic studies into the cytotoxic activity of garlic-related trisulfides in cancer cells
Published 2025“…Chapter Five investigates the cytotoxic effects of trisulfides in cancer cells, focusing on a refined library of trisulfides to identify structure-activity relationships, particularly in benzyl derivatives. …”
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An aggregated digital twin system for a human-robot collaboration manufacturing cell
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Development of a novel bioreactor and systems for suspension cell culture in biopharmaceutical production
Published 2022“…The results indicated that the anti-cancerous drug may have modulated the structure and function of the integrin which resulted in dislodging of the cells from the surface and form clumps which were viable for a week in suspension culture without increase in cell density. …”
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Immunoreactivities to α-SMA and S-100 proteins in the testis of the African four-toed Hedgehog (Atelerix albiventris)
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Investigation of the mechanisms underlying the effects of hyperglycaemia on cardiac structural and electrical remodelling
Published 2022“…Methods: Mouse embryonic stem cells (mESCs) were differentiated into pulsatile, cardiac-like cells via embryoid body (EB) formation and cultured under baseline- or high glucose conditions. …”
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A Structure-Activity Relationship Study of Dihydroajoenes as Anti-Cancer Agents
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Imaging and quantifying the different crystalline structures of polypropylene with the atomic force microscope
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Investigating the effect of frother type on froth structure, froth recovery and entrainment
Published 2015“…The froth structure is dependent on amongst other factors the type of frothers used during the separation process. …”
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An exploration of the molecular mechanisms underlying the effects of hyperglycaemia on the autorrhythmicity of cardiac-like stem cells
Published 2024“…Using a cardiac developmental cellular model, this study aimed to explore the effects of hyperglycaemia on the autorrhythmicity of mouse embryonic stem cell (mESC)-derived cardiac-like cells.…”
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Lamina-associated polypeptide 2 (LAP2) expression patterns in transformed and cancer cells
Published 2014“…The Lamina-associated polypeptide two (LAP2) proteins comprising three human isoforms, LAP2 +- LAP2β and LAP2 have been shown to provide a structural framework in the nucleus and to facilitate nuclear assembly and disassembly during the cell cycle. …”
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Antimalarial imidazopyridazines and aminopyrazines: synthesis, physicochemical optimization and structure-activity relationships
Published 2019“…Furthermore, cytotoxicity assessment of selected analogues against the Chinese Hamster Ovarian (CHO) cell line revealed that most analogues were relatively noncytotoxic (selectivity indices in the range 72 - > 874). …”
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