Understanding the mechanisms of drug resistance in enhancing rapid molecular detection of drug resistance in Mycobacterium tuberculosis by Johnson, Rabia

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Sodium, potassium adenosine triphosphatase as a potential target of the anti-tuberculosis agents, clofazimine and bedaquiline

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The application of immunological biomarkers and enhanced pathogen detection for the epidemiological characterisation of bovine tuberculosis in African Rhinoceros by Dwyer-Leonard, Rebecca Ann

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Newer and novel sputum versus non-sputum-based tools for the diagnosis of active tuberculosis in different patient sub-populations by Esmail, Aliasgar

“…Background Pulmonary tuberculosis (PTB) has a spectrum of presentation ranging from sub clinical/minimally symptomatic disease on one end, usually in community-based patients, to overt symptomatic TB with hospitalisation on the severe end of the spectrum. …”
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Counterfeiting of HIV/AIDS medicines : implications for global epidemic : recommendations for workplace programs by Norris, Gerard Benedict

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Environmental health recommendations for Multidrug-Resistant Tuberculosis in low- and middle-income countries: a systematic review by Nel, Amy

“…Despite efforts towards the management and prevention of Tuberculosis (TB) having shown some success, Multidrug-Resistant Tuberculosis (MDR-TB) may potentially compromise these endeavours. …”
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Prediction of post-tuberculosis lung damage using CT lung imaging measures among adults in Malawi by Gunsaru, Vester Poyamba

“…The burden of tuberculosis (TB) is high globally and in sub-Saharan Africa (SSA). …”
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Assessing access barriers to Tuberculosis (TB) and Antiretroviral (ARV) treatment in Mitchell's Plain, Cape Town South Africa by Mweemba, Chrispin

“…Access to health care is a very important concept which has equally important implications to the health status of individuals. However, there have been a lot of debates among researchers and policy makers on what constitutes access, and how it can be made less conceptual and more operational. …”
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Mycobacterium tuberculosis persisters at the host-pathogen interface: development and application of tools for identification and elucidating impact on host response by Obasa, Zimvo

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The molecular epidemiology of mycobacterium tuberculosis : role in understanding disease dynamics in high prevalence settings in Southern Africa region by Chihota, Violet

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The 2.7 resolution cryo-EM reconstruction of Mycobacterium tuberculosis encapsulin nanocompartment containing DyP peroxidase by Willmore, Rhys

“…One such immune response generated by humans is the use of reactive oxygen species (ROS) such as H2O2 to cause damage to M. tuberculosis. Encapsulin (from here on referred to as Enc) nanocompartments and the cargo proteins within have been implicated as persistence factors and decreased viability of cells has been shown when they are knocked out. …”
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Identification of immune correlates of natural protection against tuberculosis in a population with a high incidence of latent infection by Golakai, Hawa Jande

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Human genetic susceptibility to tuberculosis : the investigation of candidate genes influencing interferon gamma levels and other candidate genes affecting immunological pathways by Moller, Marlo

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Illuminating a neglected population: epidemiological and clinical features of silicosis and tuberculosis among former gold miners from Lesotho by Maboso, Botembetume

“…Objectives To address the problem of TB, in general and the high morbidity and mortality among exgold miners, in particular, we designed three separate studies with the following objectives: (1) To illustrate the challenges in diagnosing active TB in this setting, specifically in distinguishing pulmonary TB (past and current) from silicosis; (2) to assess the performance of the screening CXR and symptoms of cough and fever in the diagnosis of active TB disease using Xpert MTB/RIF sputum test as the reference standard; and (3) to identify predictors of silicosis, tuberculosis, and associated hypoxaemia to better understand the predictive effects of comorbidity, the determinants of severity, and health care implications. …”
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The glutamate dehydrogenase of the slow growing mycobacteria : its function in nitrogen metabolism and importance to in vitro and intracellular survival by Viljoen, Albertus Johannes

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The development of an interferon-gamma (IFNγ) assay for the diagnosis of tuberculosis in African elephants (Loxodonta africana) and black rhinoceros (Diceros bicornis)

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Riboswitch regulation of methionine metabolism and vitamin B12 uptake in mycobacteria – implications for drug susceptibility and pathogenesis by Kipkorir, Terry

“…Alterations in the genetic capacity for cobamide biosynthesis have been identified as potentially critical in the evolution of Mycobacterium tuberculosis from a putative environmental ancestor. …”
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Determination of the mechanism of synergy of SQ109 with rifampicin and isoniazid in Mycobacterium smegmatis by Manunu, Bayanika

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