Modulation of the progesterone receptor by progestogens, antiretroviral drugs and the glucocorticoid receptor by Enfield, Kim

“…The mechanism of ARV action on PR-B activity was investigated by competitive binding assays, as well as by determination of PR phosphorylation levels. …”
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Characterisation of dysregulated proteins in macrophages infected with Mycobacterium smegmatis focusing on matrix metalloproteases and their effectors by Seele, Palesa Pamela

“…Animals which can develop cavities have well-conserved MMP-1 orthologs suggesting a pivotal role of MMP-1 in cavitation. …”
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Development and Characterization of a Modified Vaccinia Ankara Vaccine Candidate Expressing the SARS-CoV-2 Spike Glycoprotein by Khumalo, Fezokuhle Ncedile

“…In Africa, the cost of vaccine manufacturing as well as the scarcity in resources for storage and distribution have all contributed to the inequitable access to vaccines and heavy reliance on donations. …”
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Characterisation of human surfactant protein A and recombinant human vimentin in their modulation of HPV16 pseudovirus infection by Carse, Sinead

“…Removal of surface HSPGs on NIKS cells decreased HPV16-PsVs cell surface binding and internalisation, while pre-incubation of HPV16-PsVs with rhVim decreased viral particle binding and internalisation to a greater extent. …”
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Isolation and characterization of novel aptamers against the CFP-10/ESAT-6 heterodimer for the development of TB diagnostic tools

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Regulated expression of the Schizosaccharomyces pombe malic enzyme gene by Van der Merwe, Marizeth

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An integrative data-analysis of miRNA-related contributions to the pathophysiology of neuropsychiatric disorders by Prinsloo, Hendrik Johannes

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Transcription regulatory networks in medulloblastoma. by Howeedy, Yasmeen Hesham

“…PRLR (prolactin receptor) and MET (met proto oncogene) up regulations supported the involvement of these patient profiles with retinopathy progression pathways as well as pathways. TFs regulating cancer progression in this subgroup included TBX1 (T box 1), CEBP( CCAAT enhancer binding protein) and CLK1 (CDC-like kinase), while the Apoptotic transcriptional regulation is through AVEN (apoptosis caspase activation inhibitor). …”
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Semi-synthesis and evaluation of fusidic acid derivatives as potential antituberculosis agents by Shanika, Petrus Siningu

“…Although TB is curable, the ability to acquire resistance to various antibiotics by the Mtb organism is well known. The emergence and spread of multidrug resistance (MDR) and extremely drug resistance (XDR) Mtb strains, along with HIV/TB co-infections, has put TB control programmes in jeopardy, particularly in developing countries. …”
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The in-silico evaluation and synthesis of silicon-based analogues of the cholinesterase inhibitor Donepezil

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The Antiatherogenic Potential of Two triterpenes from Protorhus longifolia stem bark (Benrh.) Engl.

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ASMT gene polymorphisms are associated with Autism Spectrum Disorder (ASD) symptom severity in a South African population by De Waal, Margaretha

“…However both the mode of action of supplemental melatonin, as well as whether melatonin deficiency is common in ASD, remains unclear. …”
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Identification of regulatory elements mediating responses of SOD and cystatin transcripts to salt stress and nitric oxide in soybean nodules by Jacobs, Frans Alexander

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Screening of the human tumor necrosis factor (TNF) gene and its receptor 1 (TNFR1) gene for DNA alterations and the subsequent investigation of these and an IL12p40 polymorphism fo... by Lampel, Netanya

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Investigation of Neurexin 2 as a candidate for Parkinson's Disease by Cuttler, Katelyn

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Development of SNAP-tag based fusion proteins as novel auristatin F-containing immunoconjugates and photoimmunotheranostics in the detection and treatment of triple-negative breast... by Mungra, Neelakshi

“…Integration of the fluorescent dye Alexa Fluor 488 into the fusion proteins was carried out to investigate the self-labeling activity of the SNAP-tag moiety, as well as to provide qualitative and quantitative insights into the binding potential of the antibody fragments towards their cognate antigens. …”
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Assessing the effects of two plants containing psychoactive compounds on the SH-SY5Y Parkinson’s disease neuroblastoma cell model

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Covalent immobilisation of β-Galactosidase from Escherichia coli to commercially available magnetic nanoparticles for the removal of lactose from milk by Pretorius, Chantelle

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The employment recruitment and promotion process: legal regulation and practice by Adonis, Tanya

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