Channels Synthesis, antimalarial evaluation, Ç-hematin inhibition, and in silico and in vitro ADMET profiling of 4-aminoquinoline-hydroxypyridinone hybrids
Integration of In Silico and In Vitro ADMET properties in lead identification and optimization of compounds for the treatment of parasitic diseases
New aminoquinoline antimalarial cysteine protease inhibitors based on the isatin natural product scaffold
In vitro efficacy assessment of targeted antimalarial drugs synthesized following in silico design
Molecular Docking and ADMET Analysis of Selected Polyphenols Targeting Acetylcholinesterase: An In Silico Approach
In silico docking and ADMET studies on clinical targets for type 2 diabetes correlated to in vitro inhibition of pancreatic alpha-amylase and alpha-glucosidase by rutin, caffeic acid, p-coumaric acid, and vanillin
In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid
Antioxidant, antibacterial, in vitro, and in silico α-glucosidase inhibition activities and chemical profiling of Usnea cornuta Korb
In silico docking and ADMET studies on clinical targets for type 2 diabetes correlated to in vitro inhibition of α-glucosidase and pancreatic α-amylase by curcumin, 18α-glycyrrhetinic acid, rosmarinic acid, and quercetin
In Silico Pharmacokinetic Profile and Antimalarial Efficacy of 3-Chloro-4-(4-Chlorophenoxy)Aniline
In silico design, synthesis and in vitro evaluation of antimitotic agents
Design and synthesis of dual-active heterocyclic yybrid inhibitors for β-Hematin and plasmodium falciparum N-Myristoyltransferase
Synthesis and investigation of benzimidazole and carbazole ß-haematin inhibiting scaffolds with antimalarial activity
Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
Antibacterial and Antioxidant Activities, in silico Molecular Docking, ADMET and DFT Analysis of Compounds from Roots of Cyphostemma cyphopetalum
Anti-cancer and anti-malarial 4-aminoquinoline derivatives : synthesis and solid-state investigations
Synthesis and antiplasmodial structure-activity relationships for some novel 4-aminoquinolines and 5-chlorobenzimidazoles
In silico Study of Antiviral Activity of Polyphenol Compounds from Ocimum basilicum by Molecular Docking, ADMET, and Drug-Likeness Analysis
Development of aminoquinoline-benzimidazole hybrids and their organometallic complexes as antimicrobial agents against Plasmodium falciparum and Mycobacterium tuberculosis
Synthesis, characterisation and pharmacological evaluation of silicon-containing aminoquinoline organometallic complexes as antiplasmodial, antitumor and antimycobacterial agents
Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles
Design and synthesis of novel antimalarial agents
Expanding the versatility of aminoquinoline organometallic complexes as anticancer and antibacterial agents
Synthesis of novel 1,2,4-oxadiazole-isoxazoline hybrids and their in silico potential with adenosine receptors
Inhibition of lysine-specific demethylase 1 as an antimalarial target by polyamine analogues
Synthesis and biological evaluation of thiazole and metergoline derivatives as antimycobacterial and antiplasmodial agents
Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles
Small molecule inhibitors of parasitic enzymes
Antiplasmodial neolignans from Trema orientalis : identification, synthesis and analogue generation.
Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles
Design, synthesis and evaluation of potential dual drugs targeting the haemoglobin degradation pathway in the malaria parasite Plasmodium falciparum
Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles
Synthesis of aminomethylthiazole analogues for evaluation as antiplasmodial agents
Synthesis and Antimalarial evaluation of Gold Thiosemicarbazone Complexes and Polyamine-Thiosemicarbazone Dendrimers
Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery
A medicinal chemistry approach to drug repositioning in the treatment of tuberculosis and malaria
Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity
Antiprotozoal quinolines containing electrophilic moieties
Novel Antimalarial and Antitubercular Agents Based on Natural Products
Isolation and characterization of African marine natural products and repositioning of the natural product antibiotic fusidic acid and privileged benzimidazole scaffold for tuberculosis and malaria
Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
Exploring the potential of xanthene derivatives as inhibitors of trypanothione reductase and resistance reversal agents
Investigating the chemical space and metabolic bioactivation of natural products and cross-reactivity of chemical inhibitors in CYP450 phenotyping
Ferrocenic metal chelators : synthesis, biological and electrochemical studies
Piperazine-based pyrido[1,2-a]benzimidazoles: synthesis and pharmacological evaluation as potential antimalarial and antischistosomal agents
Bioactive chloroquine-based ligands and their gold complexes as potential novel antimalarial agents
Synthesis and evaluation of D-cycloserine analogues against mycobacterium tuberculosis
Antimalarial drug rescue through safety improvement: design, synthesis and evaluation of amaodiaquine analogues
Developing methods to prioritize in vitro drug combinations against Mycobacterium tuberculosis: fusidic acid as potential combination partner with known antitubercular agents
