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Integration of In Silico and In Vitro ADMET properties in lead identification and optimization of compounds for the treatment of parasitic diseases

Parasitic infections are the major causes of illness and death in tropical regions especially in Africa. The main parasitic diseases include leishmaniasis, filariasis, malaria, river blindness, Chagas disease and schistosomiasis. With the absence of vaccines, treatment relies mainly on chemotherapy...

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Bibliographic Details
Main Author: Thelingwani, Roslyn
Other Authors: Chibale, Kelly
Format: Thesis
Language:English
Published: Department of Chemistry 2014
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