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Antimycobacterial 2-aminoquinazolinones and benzoxazole-based oximes: synthesis, biological evaluation, physicochemical profiling and supramolecular derivatization
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Synthesis, characterisation, structure-activity and structure-property relationship studies of quinazolinones as antimycobacterial agents
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Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles
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The application of the Multi-Component Reaction (MCR) strategy in the design and synthesis of new antiplasmodial and antimycobacterial agents
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Mono- and polynuclear Ferrocenyl-derived complexes: synthesis, characterisation and biological evaluation as
antimycobacterial and antiplasmodial agents
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Synthesis and structure-activity relationships of ring D alkyl 19-norsteroids
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Synthesis and structure activity relationships of ring D modified steroidal hormones
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Synthesis, characterisation and pharmacological evaluation of silicon-containing aminoquinoline organometallic complexes as antiplasmodial, antitumor and antimycobacterial agents
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Synthesis and antiplasmodial structure-activity relationships for some novel 4-aminoquinolines and 5-chlorobenzimidazoles
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Design, synthesis and characterization of water soluble heterobimetallic complexes and their evaluation as aqueous biphasic hydroformylation catalysts
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Synthesis and structure-activity relationship studies of novel anti-infectives for cross screening in tuberculosis and malaria disease models
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Discovery of benzamides and triarylimidazoles active against Plasmodium falciparum via haemozoin inhibition : high throughput screening, synthesis and structure-activity relationships
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The antimycobacterial activity of phytocannabinoids
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Characterisation, synthesis and antimycobacterial activity of naphthoquinones isolated from Euclea natalensis
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Structure activity and structure property relationships of antimalarial imidazopyridazines
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Synthesis, antimalarial evaluation and structure-activity relationship in a series of dibenzlmethylamine (Dibemethin) derivatives of 4-amino-7-chloroquinoline
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Synthesis and structure-activity studies of skeletally modified estradiol analogues
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Synthesis, pharmacological and solubility evaluation of antiplasmodial pyrido[1,2-a]benzimidazoles with cyclic and functionalized amine side chain substituents
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Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles
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Synthesis and biological activity of ajoenes with increased aqueous solubility
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Design, synthesis, and structure-activity relationship studies of dual Plasmodium falciparum phosphatidylinositol 4-kinase and cGMP-dependent protein kinase inhibitors
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Synthesis of mixed ligand, water soluble square planar platinum (II) complexes and an investigation of their association with haematin and potential to inhibit the formation of synthetic malaria pigment
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Structure-activity relationships in Werner clathrates
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Synthesis, Structure, and Catalytic Activity of Bimetallic Rhodium Complexes in the Hydroformylation and Allylic Oxidation of Alkenes
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Synthesis and biological evaluation of thiazole and metergoline derivatives as antimycobacterial and antiplasmodial agents
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Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles
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Small molecule inhibitors of parasitic enzymes
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Antiplasmodial neolignans from Trema orientalis : identification, synthesis and analogue generation.
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Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles
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Design, synthesis and evaluation of potential dual drugs targeting the haemoglobin degradation pathway in the malaria parasite Plasmodium falciparum
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Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles
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Synthesis of aminomethylthiazole analogues for evaluation as antiplasmodial agents
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Synthesis and Antimalarial evaluation of Gold Thiosemicarbazone Complexes and Polyamine-Thiosemicarbazone Dendrimers
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Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery
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A medicinal chemistry approach to drug repositioning in the treatment of tuberculosis and malaria
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Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity
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Antiprotozoal quinolines containing electrophilic moieties
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Novel Antimalarial and Antitubercular Agents Based on Natural Products
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Isolation and characterization of African marine natural products and repositioning of the natural product antibiotic fusidic acid and privileged benzimidazole scaffold for tuberculosis and malaria
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Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
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Exploring the potential of xanthene derivatives as inhibitors of trypanothione reductase and resistance reversal agents
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Investigating the chemical space and metabolic bioactivation of natural products and cross-reactivity of chemical inhibitors in CYP450 phenotyping
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Ferrocenic metal chelators : synthesis, biological and electrochemical studies
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Piperazine-based pyrido[1,2-a]benzimidazoles: synthesis and pharmacological evaluation as potential antimalarial and antischistosomal agents
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Bioactive chloroquine-based ligands and their gold complexes as potential novel antimalarial agents
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Synthesis and evaluation of D-cycloserine analogues against mycobacterium tuberculosis
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Antimalarial drug rescue through safety improvement: design, synthesis and evaluation of amaodiaquine analogues
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Developing methods to prioritize in vitro drug combinations against Mycobacterium tuberculosis: fusidic acid as potential combination partner with known antitubercular agents