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Synthesis, pharmacological and solubility evaluation of antiplasmodial pyrido[1,2-a]benzimidazoles with cyclic and functionalized amine side chain substituents
Malaria continues to cause significant morbidity and mortality globally, especially in sub-Saharan Africa where the disease is endemic. Widespread resistance by Plasmodium parasites to chloroquine and sulphadoxine-pyrimethamine, once mainstays of malaria treatment, has further set back control effor...
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| Format: | Thesis |
| Language: | English |
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Department of Chemistry
2017
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