Channels Design, synthesis and evaluation of potential dual drugs targeting the haemoglobin degradation pathway in the malaria parasite Plasmodium falciparum
High-throughput prioritization of putative drug targets in the malaria parasite, Plasmodium falciparum
Inhibition of the histone deacetylase family as a drug target in the human malaria parasite, plasmodium falciparum
Structural and functional validation of S-adenosylmethionine decarboxylase as a novel drug target in the malaria parasite, Plasmodium falciparum
Biochemical and structural characterization of novel drug targets regulating polyamine biosynthesis in the human malaria parasite, Plasmodium falciparum
The interaction of verapamil with the human malaria parasite : Plasmodium falciparum
Probing the chemical biology involved in the haem detoxification pathway of the human malaria parasite, plasmodium falciparum
Biochemical characterisation of putrescine and spermidine uptake as a potential therapeutic target against the human malaria parasite, Plasmodium falciparum
Transcriptional and post-transcriptional gene regulatory mechanisms in the malaria parasite, Plasmodium falciparum
Characterising the role of actin and PI (3) kinases in endocytosis in the malaria parasite Plasmodium falciparum
Transcriptome- and proteome-wide responses to putrescine depletion in the human malaria parasite, Plasmodium falciparum
In silico prediction of host-pathogen protein - protein interactions in the malaria parasite, Plasmodium falciparum
DETERMINANTS OF RESPONSES TO ANTIMALARIAL DRUGS IN CHILDREN WITH UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA
Proteolysis-targeting chimeras as a novel strategy for targeting epigenetic mechanisms in Plasmodium falciparum parasites
Epigenetic repression of gene expression controls the initial phases of gametocytogenesis in the malaria parasite, Plasmodium falciparum
Biochemical and immunochemical investigation of some South African strains of the human malaria parasite, Plasmodium falciparum
Development of analytical techniques for probing the effects of -haematin inhibiting compounds on the malaria parasite Plasmodium falciparum
Characterisation of Plasmodium falciparum proteins expressed on infected red blood cell surfaces as potential drug targets for severe malaria therapy
Investigating phenotypic differences of Plasmodium falciparum parasites following exposure to classical antimalarial drugs
Studies on the degradation of haemoglobin
Target indicators and mechanistic function of epidrugs with activity against multiple stages of Plasmodium falciparum parasites
Coenzyme a biosynthesis and utilization in Plasmodium falciparum : drug targets for antimalarial chemotherapy
Large–scale data–driven network analysis of human–plasmodium falciparum interactome: extracting essential targets and processes for malaria drug discovery
Radiolabelled antibodies as a detection tool for malaria parasite (Plasmodium falciparum 3D7)- infected human erythrocytes
Development of transgenic Plasmodium falciparum parasites for K+ channel functional investigation
Synthesis and biological evaluation of thiazole and metergoline derivatives as antimycobacterial and antiplasmodial agents
Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles
Small molecule inhibitors of parasitic enzymes
Antiplasmodial neolignans from Trema orientalis : identification, synthesis and analogue generation.
Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles
Design, synthesis and evaluation of potential dual drugs targeting the haemoglobin degradation pathway in the malaria parasite Plasmodium falciparum
Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles
Synthesis of aminomethylthiazole analogues for evaluation as antiplasmodial agents
Synthesis and Antimalarial evaluation of Gold Thiosemicarbazone Complexes and Polyamine-Thiosemicarbazone Dendrimers
Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery
A medicinal chemistry approach to drug repositioning in the treatment of tuberculosis and malaria
Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity
Antiprotozoal quinolines containing electrophilic moieties
Novel Antimalarial and Antitubercular Agents Based on Natural Products
Isolation and characterization of African marine natural products and repositioning of the natural product antibiotic fusidic acid and privileged benzimidazole scaffold for tuberculosis and malaria
Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
Exploring the potential of xanthene derivatives as inhibitors of trypanothione reductase and resistance reversal agents
Investigating the chemical space and metabolic bioactivation of natural products and cross-reactivity of chemical inhibitors in CYP450 phenotyping
Ferrocenic metal chelators : synthesis, biological and electrochemical studies
Piperazine-based pyrido[1,2-a]benzimidazoles: synthesis and pharmacological evaluation as potential antimalarial and antischistosomal agents
Bioactive chloroquine-based ligands and their gold complexes as potential novel antimalarial agents
Synthesis and evaluation of D-cycloserine analogues against mycobacterium tuberculosis
Antimalarial drug rescue through safety improvement: design, synthesis and evaluation of amaodiaquine analogues
Developing methods to prioritize in vitro drug combinations against Mycobacterium tuberculosis: fusidic acid as potential combination partner with known antitubercular agents
