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Development of analytical techniques for probing the effects of -haematin inhibiting compounds on the malaria parasite Plasmodium falciparum

Phenotypic screening for novel compounds that inhibit the growth of the malaria parasite remains one of the most effective ways to identify novel antimalarial drugs. Subsequent deconvolution of the drug target and mechanism of action (MoA) are a vital part of the drug development process. This is of...

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Bibliographic Details
Main Author: Maepa, Makgalanoto
Other Authors: Wiesner, Joachim
Format: Thesis
Language:Eng
Published: Department of Medicine 2024
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