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Synthesis of aminomethylthiazole analogues for evaluation as antiplasmodial agents
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Strategies towards the synthesis of prostaglandin analogues
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Design and synthesis of rotational analogues of estradiol
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The synthesis and evaluation of new organometallic benzimidazole Complexes as antiplasmodials
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Synthesis of delta-1(9)-octalinols and their analogues
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Synthesis of 2,2-dipyridylamine organometallic complexes for antiplasmodial application
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Mono- and multinuclear PGM complexes containing thiosemicarbazones synthesis, characterization and antiplasmodial evaluation
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Synthesis of analogues of mycothiol as possible inhibitors of enzymes in the biosynthesis of mycothiol
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Synthesis and structure-activity studies of skeletally modified estradiol analogues
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Synthesis and evaluation of D-cycloserine analogues against mycobacterium tuberculosis
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Synthesis and antiplasmodial structure-activity relationships for some novel 4-aminoquinolines and 5-chlorobenzimidazoles
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Synthesis, biological activity and physicochemical properties evaluation of antiplasmodial pyrimido[1,2-a]benzimidazoles
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The application of the Multi-Component Reaction (MCR) strategy in the design and synthesis of new antiplasmodial and antimycobacterial agents
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Mono- and polynuclear Ferrocenyl-derived complexes: synthesis, characterisation and biological evaluation as
antimycobacterial and antiplasmodial agents
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Synthesis, characterisation and pharmacological evaluation of silicon-containing aminoquinoline organometallic complexes as antiplasmodial, antitumor and antimycobacterial agents
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Towards the total synthesis of novenamine and its analogues with modifications at C-4 and C-5
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Flow and Microwave Induced Pellizzari Reactions: Synthesis of Heterocyclic Analogues of the Benzoxazepine Antipsychotic Agents Loxapine and JL-13
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Synthesis, pharmacological and solubility evaluation of antiplasmodial pyrido[1,2-a]benzimidazoles with cyclic and functionalized amine side chain substituents
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Studies on the synthesis, cyclodextrin inclusion and biological activity of ajoene analogues as potentially novel anti-cancer agents
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Synthesis of side-chain-modified mycothiol analogues incorporating carbazole quinones, and evaluation as inhibitors of enzymes in the Mycobacteria
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Quinoline-triazole half-sandwich iridium(III) complexes: Synthesis, antiplasmodial activity and preliminary transfer hydrogenation studies
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The synthesis of analogues and bioisosteres of the acetylcholinesterase inhibitor donepezil in an attempt to identify novel anti-Alzheimer’s agents
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Attempted routes towards the synthesis of fluorinated analogues of ornithine as potential inhibitors of ornithine decarboxylase
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Synthesis and biological evaluation of novel ferroquine and phenylequine analogues
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Synthesis and biological evaluation of thiazole and metergoline derivatives as antimycobacterial and antiplasmodial agents
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Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles
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Small molecule inhibitors of parasitic enzymes
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Antiplasmodial neolignans from Trema orientalis : identification, synthesis and analogue generation.
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Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles
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Design, synthesis and evaluation of potential dual drugs targeting the haemoglobin degradation pathway in the malaria parasite Plasmodium falciparum
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Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles
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Synthesis of aminomethylthiazole analogues for evaluation as antiplasmodial agents
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Synthesis and Antimalarial evaluation of Gold Thiosemicarbazone Complexes and Polyamine-Thiosemicarbazone Dendrimers
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Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery
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A medicinal chemistry approach to drug repositioning in the treatment of tuberculosis and malaria
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Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity
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Antiprotozoal quinolines containing electrophilic moieties
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Novel Antimalarial and Antitubercular Agents Based on Natural Products
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Isolation and characterization of African marine natural products and repositioning of the natural product antibiotic fusidic acid and privileged benzimidazole scaffold for tuberculosis and malaria
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Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
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Exploring the potential of xanthene derivatives as inhibitors of trypanothione reductase and resistance reversal agents
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Investigating the chemical space and metabolic bioactivation of natural products and cross-reactivity of chemical inhibitors in CYP450 phenotyping
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Ferrocenic metal chelators : synthesis, biological and electrochemical studies
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Piperazine-based pyrido[1,2-a]benzimidazoles: synthesis and pharmacological evaluation as potential antimalarial and antischistosomal agents
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Bioactive chloroquine-based ligands and their gold complexes as potential novel antimalarial agents
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Synthesis and evaluation of D-cycloserine analogues against mycobacterium tuberculosis
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Antimalarial drug rescue through safety improvement: design, synthesis and evaluation of amaodiaquine analogues
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Developing methods to prioritize in vitro drug combinations against Mycobacterium tuberculosis: fusidic acid as potential combination partner with known antitubercular agents
