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Author: Jacobs, Leon

  • Author: Hamann, Anton Ruben
  • Author: Hay, Jonathan Bruce
  • Author: Venter, Jana
  • Author: Wolff, Karin
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    Synthesis of fused heterocyclic aromatic compounds as potential antiplasmodial agents
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    Synthesis and biological evaluation of novel ferroquine and phenylequine analogues

Author: Clements, Monica Jade

  • Author: Hamann, Anton Ruben
  • Author: Hay, Jonathan Bruce
  • Author: Venter, Jana
  • Author: Wolff, Karin
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    Investigating the formation of multicomponent crystals of antiplasmodial agents

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    Design and synthesis of dual-active heterocyclic yybrid inhibitors for β-Hematin and plasmodium falciparum N-Myristoyltransferase
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    X-ray and NMR spectropscopic studies of selected heterocyclic compounds of phosphorus and nitrogen
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    Studies in the synthesis of benzoxazole compounds
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    Carbene and coordination complexes of gold, palladium, platinum and manganese derived from N-containing heterocycles
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    Gold N-heterocyclic carbene complexes as anti-cancer agents : Au-Se interactions and solubility
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    Synthesis and characterization of palladium complexes exhibiting hemilabile properties
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    N-heterosikliese karbeenkomplekse van groep 10 metale : nuwe moontlikhede
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    Resorcin[4]arene based N-heterocyclic carbenes as catalysts for carbon-carbon formation
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    Development of new metallo-drugs for haemozoin inhibition
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    Green gold : valorising wax by-products from commercial cannabis sativa processing
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    Utilisation of various bonding modes of nitrogen-rich heterocycles in gold(I) chemistry
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    Late transition metal complexes based on novel pyridine-triazole ligands as catalyst precursors in ethylene oligomerization and transfer hydrogenation reactions
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    New gold(I) and gold(III) coordination complexes derived from N and S heterocycles
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    Novel palladium (II) complexes belonging to a family of potential catalytic precursors
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    Identification of drugs by controlled thin-layer chromatography
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    Validation of radiochemical purity analysis methods used in two tertiary public hospitals in South Africa
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    Design and synthesis of dual-heterocyclic hybrid inhibitors for malaria and cancer
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    Novel Piperidone and Bispidine Derivatives: A New Approach in Cancer Therapy
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    Synthesis of an 8-membered oxygen-containing benzo-fused heterocycle using flow technologies
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    The synthesis of novel kinase inhibitors using click chemistry
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    Carbene ligand and complex design directed towards application in synthesis and homogeneous catalysis
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    Structure and synthesis of some phosphorus compounds of potential biological activity
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    The effect of some aromatic compounds on the physiology of the rat and on certain microorganisms
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    Analysis of volatile organic compounds in water by sorptive extraction and gas chromatography - mass spectrometry

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    Design, synthesis and biological activity studies of 1-aryl-3-(4-methoxybenzyl)ureas as proposed irreversible GSK-3 inhibitors in Alzheimer’s disease therapeutic development
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    Design and synthesis of benzazole ureas as proposed irreversible GSK-3β inhibitors
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    Design and synthesis of Covalent Kinase Inhibitors Utilising Novel Electrophiles
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    In vitro effect of selected medicinal plants on β-amyloid induced toxicity in neuroblastoma cells
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    Selective GSK3β inhibition mediates an Nrf2-independent anti-inflammatory microglial response
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    Role of glycogen synthase kinase 3 (GSK-3) and its substrate proteins in the development of cardiomyopathy associated with obesity and insulin resistance
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    ISOLATION OF DIOSGENIN FROM Smilax kraussiana MEISN EX. KRAUSS AND SYNTHESIS OF ITS DERIVATIVES AS ANTICANCER AGENTS
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    Scaffold manipulation for the synthesis of novel, potentially irreversible Akt inhibitors
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    In vitro modelling of cellular haemozoin and inhibition by β-haematin inhibitors and their derivatives
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    Do metals contribute to the establishment of Alzheimer's disease?
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    The relationship between some genetic and environmental factors in the etiology of Alzheimer's disease
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    The design, synthesis and biological evaluation of novel compounds against biomarkers of Alzheimer’s disease
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    Investigating Tau pathology in an in vitro model for Alzheimer’s disease
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    The characterization of 17β-hydroxysteroid dehydrogenase type 2 (17βHSD2) activity towards novel C19 substrates.
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    Investigating the effects of enhanced catecholamine stimulation in stem cell-derived cardiomyocytes
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    Lipopolysaccharide promotes hypercoagulability in Alzheimer’s type dementia
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    The effects of apathy and depression on cognitive and functional outcomes in Alzheimer's disease
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    High throughput in silico screening and in vitro testing of polypharmacological bromodomain 4 and cancer associated kinase inhibitors
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    Communication, cognitive functioning, and feeding and swallowing information needs of caregivers of individuals diagnosed with alzheimer’s disease within a support group setting
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    The design and synthesis of novel HIV-1 non-nucleoside reverse transcriptase inhibitors
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    Assessing the acetylcholinesterase inhibitory potential of novel pharmacophores for potential treatment of Alzheimer’s disease
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    Thermodynamic optimisation of solar thermal brayton cycle models and heat exchangers using particle swarm algorithm
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    An investigation of the β-Carotene status of Holstein cows in South Africa
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    Association of Gut Microbiota Composition with Alzheimer’s-Like Disease in A Rat Model

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