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In vitro modelling of cellular haemozoin and inhibition by β-haematin inhibitors and their derivatives

The discovery of new β-haematin inhibitors has become one focus for researches in response to the resistance of P. falciparum malaria parasites that emerged towards well-known antimalarials. While hundreds of new β-haematin inhibitors have been discovered using detergent mediated high-throughput scr...

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Bibliographic Details
Main Author: Openshaw, Roxanne
Other Authors: Egan, Timothy John
Format: Thesis
Language:English
Published: University of Cape Town 2021
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