Pharmacogenetics of resistant hypertension: evaluating the role of genetic variation in ABCB1, ADBR1, CES1, CYP3A4, CYP3A5, NEDD4L, NOS3, NR3C2 and SCNN1B among South African hypertensive patient
Prevalence of SLCO1B1 single nucleotide variations, and their association with statin intolerance in hypercholesterolaemic patients in Gauteng, South Africa
Associations of CYP2B6, CYP2C19, and CYP2D6 isoforms and phenoconversion with sertraline pharmacokinetics
CYP4B1 Expression in Breast Cancer: An Immunohistochemical Study with Complementary in silico Analyses
A structure/function investigation into baboon cytochrome P450 side-chain cleavage (CYP11A1)
Familial isolated 17,20-lyase deficiency in three siblings caused by a CYP17A1 mutation
The prevalence of 3-hydroxy-3-methylglutaryl-Coenzyme a reductase variants in hypercholesterolaemic patients with statin intolerance
Construction and analysis of a kinetic model of the ovine adrenal steroidogenic subsystem comprising of CYP17 and 3β-HSD
The impact of the cytochrome CYP2C9*2 and *3 polymorphisms in the South African Caucasian population on warfarin therapy protocols
Multi-omics and metabolic flux modeling reveal that macrophage CYP27A1-derived 26-hydroxycholesterol drives immunosuppression and cancer malignancy
Identification of two CYP17 alleles in the South African Angora goat
ABCB1 Polymorphism in HIV-Infected Individuals Taking Antiretroviral Drugs
Pharmacogenetics of CYP2D6 and CYP2C19 as a pre-prescription tool for drug efficacy and toxicity in a demographically-representative sample of theSouth African population
Genetic association and computational analysis of CYP2R1 gene polymorphisms rs2060793 and rs12794714 with vitamin D deficiency and acute myocardial infarction in the Bangladeshi population: A case control study
Inhibitory effect of selected herbal supplements on CYP450-mediated metabolism : an in vitro approach
The influence of dual CYP17 expression on adrenal steroidogenesis in the South African Angora Goat
Comparison of two CYP17 isoforms : implications for cortisol production in the South African Merino
Investigating genetic variants in ADCYAP1, ADCYAP1R1, and BRSK2 in relation to the trajectory of posttraumatic stress symptoms
RNAi targeting ABCB1-like efflux transporters improves miticide efficacy in resistant mites
HIV Viremia Is associated With APOL1 Variants and Reduced JC-Viruria
An insertion mutation in ABCB4 is associated with gallbladder mucocele formation in dogs
Vol 3, No 1 (2025)
Investigating the chemical space and metabolic bioactivation of natural products and cross-reactivity of chemical inhibitors in CYP450 phenotyping
Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction
