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Associations of genetic variants in ABCB1, ABCG2, CYP3A4, CYP3A5, and SLCO1B1 with statin-associated muscle symptom (SAMS) in South African populations

Background: Dyslipidaemia, particularly elevated plasma LDL-cholesterol levels, is a key modifiable risk factor for cardiovascular disease (CVD). Statins recognized as LDL-c lowering drugs, have traditionally been the cornerstone in dyslipidaemia treatment and are reported to reduce CVD mortality by...

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Bibliographic Details
Main Author: Lusiki, Zizo
Other Authors: Dandara, Collet
Format: Thesis
Language:Eng
Published: Department of Pathology 2025
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