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Overexpression of cofactor of BRCA1 in HepG2 cells: A step towards understanding the role of COBRA1 in hepatocellular carcinoma

Cofactor of BRCA1 (COBRA1) is a BRCA-1 interacting protein that represents one of the four subunits of the negative elongation factor (NELF) complex. NELF is known by its ability to stall RNA Polymerase II during the early phase of transcription elongation, resulting in repressed transcription of se...

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Bibliographic Details
Main Author: Masad, Razan Jamil
Format: Thesis
Published: AUC Knowledge Fountain 2016
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