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Fabrication of electrospun nanofibers made of watermelon peel extract and PVA and investigating their antioxidant and antibacterial activities
Food waste has become a huge problem globally since thousands of different food items are wasted all over the world which affects our environment severely due to the emissions of greenhouse gas due to anaerobic decomposition and leakage at the garbage. Fruit wastes like the peels and seeds are a maj...
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| Format: | Thesis |
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AUC Knowledge Fountain
2019
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| _version_ | 1867613419166760960 |
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| access_status_str | Open Access |
| author | Soliman, Wafaa |
| author_browse | Soliman, Wafaa |
| author_facet | Soliman, Wafaa |
| author_sort | Soliman, Wafaa |
| collection | Thesis |
| dc_rights_str_mv | The author retains all rights with regard to copyright. The author certifies that written permission from the owner(s) of third-party copyrighted matter included in the thesis, dissertation, paper, or record of study has been obtained. The author further certifies that IRB approval has been obtained for this thesis, or that IRB approval is not necessary for this thesis. Insofar as this thesis, dissertation, paper, or record of study is an educational record as defined in the Family Educational Rights and Privacy Act (FERPA) (20 USC 1232g), the author has granted consent to disclosure of it to anyone who requests a copy. The author has granted the American University in Cairo or its agents a non-exclusive license to archive this thesis, dissertation, paper, or record of study, and to make it accessible, in whole or in part, in all forms of media, now or hereafter known. |
| description | Food waste has become a huge problem globally since thousands of different food items are wasted all over the world which affects our environment severely due to the emissions of greenhouse gas due to anaerobic decomposition and leakage at the garbage. Fruit wastes like the peels and seeds are a major contribution to the waste products thrown everyday especially in juice industries. The antioxidant and antimicrobial activities of food wastes have been of great interest nowadays due to oxidative stress and antibiotic resistance problems. However the stability of the fruits or vegetables wastes was a challenge to perform these activities under controlled release and remains stable for long period of time. Therefore, the purpose of this study is to extract watermelon peel using different solvents and examines its total phenolic content using Folin & Ciocalteu's method. The best solvent showed the highest TPC was methanol and selected for the tests below. The watermelon peel extract (WPE) was mixed with polyvinyl alcohol (PVA) and used to fabricate nanofibers (WPE/PVA). To the best of our knowledge WPE/PVA nanofibers have never been reported before. The main motivation behind this fabrication process is to enhance the antioxidant and antibacterial activities of WPE and more importantly is to effectively use such fruit waste at nanoscale that gives the WPE higher stability and controlled release that reached 72 hours. After successful preparation of WPE/PVA nanofibers several parameters were carefully controlled such as applied voltage, solution flow rate, and distance from the needle to the collector and needle diameter. The WPE/PVA nanofibers were fabricated at different concentrations 0.1%, 0.5%, 1% and 2.5% of the PVA weight. All the concentrations showed 100% ± 5 entrapment efficiency. The antioxidant and antibacterial activities were effectively enhanced in WPE/PVA nanofibers where the IC50 of the WPE/PVA nanofibers was 0.12 mg/mL while the IC50 of the WPE alone was 0.55 mg/mL so the activity was increased approximately 22% in the WPE/PVA nanofibers. While in the antibacterial activity the WPE/PVA nanofibers showed 83.5 ± 0.9% inhibition of the E.coli, however it showed in the WPE 70.3 ± 4.2% inhibition of the E.coli therefore the WPE/PVA nanofibers is 1.2 folds higher activity that WPE. While for S. aureus the WPE/PVA nanofibers showed 94 ± 0.8% inhibition, however it showed in the WPE 83.5 ± 1.12% inhibition of the therefore, the WPE/PVA nanofibers is 1.12 folds higher activity than that of WPE. The PVA fibers (unloaded) showed no significant inhibition activity in both E.coli and S. aureus. Characterization of the waste content like phenolics, FTIR, SEM... etc before and after Nano-formulation were done. |
| format | Thesis |
| id | oai:fount.aucegypt.edu:etds-2597 |
| institution | American University in Cairo (Egypt) |
| last_indexed | 2026-06-10T12:35:50.652Z |
| license_str | Other — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from AUC Knowledge Fountain — bepress |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | AUC Knowledge Fountain |
| publisherStr | AUC Knowledge Fountain |
| record_format | dspace |
| source_str | AUC Knowledge Fountain — bepress |
| spelling | oai:fount.aucegypt.edu:etds-2597 Fabrication of electrospun nanofibers made of watermelon peel extract and PVA and investigating their antioxidant and antibacterial activities Soliman, Wafaa Food waste has become a huge problem globally since thousands of different food items are wasted all over the world which affects our environment severely due to the emissions of greenhouse gas due to anaerobic decomposition and leakage at the garbage. Fruit wastes like the peels and seeds are a major contribution to the waste products thrown everyday especially in juice industries. The antioxidant and antimicrobial activities of food wastes have been of great interest nowadays due to oxidative stress and antibiotic resistance problems. However the stability of the fruits or vegetables wastes was a challenge to perform these activities under controlled release and remains stable for long period of time. Therefore, the purpose of this study is to extract watermelon peel using different solvents and examines its total phenolic content using Folin & Ciocalteu's method. The best solvent showed the highest TPC was methanol and selected for the tests below. The watermelon peel extract (WPE) was mixed with polyvinyl alcohol (PVA) and used to fabricate nanofibers (WPE/PVA). To the best of our knowledge WPE/PVA nanofibers have never been reported before. The main motivation behind this fabrication process is to enhance the antioxidant and antibacterial activities of WPE and more importantly is to effectively use such fruit waste at nanoscale that gives the WPE higher stability and controlled release that reached 72 hours. After successful preparation of WPE/PVA nanofibers several parameters were carefully controlled such as applied voltage, solution flow rate, and distance from the needle to the collector and needle diameter. The WPE/PVA nanofibers were fabricated at different concentrations 0.1%, 0.5%, 1% and 2.5% of the PVA weight. All the concentrations showed 100% ± 5 entrapment efficiency. The antioxidant and antibacterial activities were effectively enhanced in WPE/PVA nanofibers where the IC50 of the WPE/PVA nanofibers was 0.12 mg/mL while the IC50 of the WPE alone was 0.55 mg/mL so the activity was increased approximately 22% in the WPE/PVA nanofibers. While in the antibacterial activity the WPE/PVA nanofibers showed 83.5 ± 0.9% inhibition of the E.coli, however it showed in the WPE 70.3 ± 4.2% inhibition of the E.coli therefore the WPE/PVA nanofibers is 1.2 folds higher activity that WPE. While for S. aureus the WPE/PVA nanofibers showed 94 ± 0.8% inhibition, however it showed in the WPE 83.5 ± 1.12% inhibition of the therefore, the WPE/PVA nanofibers is 1.12 folds higher activity than that of WPE. The PVA fibers (unloaded) showed no significant inhibition activity in both E.coli and S. aureus. Characterization of the waste content like phenolics, FTIR, SEM... etc before and after Nano-formulation were done. 2019-01-08T08:00:00Z thesis application/pdf https://fount.aucegypt.edu/etds/1562 https://fount.aucegypt.edu/context/etds/article/2597/viewcontent/Thesis_20final.pdf The author retains all rights with regard to copyright. The author certifies that written permission from the owner(s) of third-party copyrighted matter included in the thesis, dissertation, paper, or record of study has been obtained. The author further certifies that IRB approval has been obtained for this thesis, or that IRB approval is not necessary for this thesis. Insofar as this thesis, dissertation, paper, or record of study is an educational record as defined in the Family Educational Rights and Privacy Act (FERPA) (20 USC 1232g), the author has granted consent to disclosure of it to anyone who requests a copy. The author has granted the American University in Cairo or its agents a non-exclusive license to archive this thesis, dissertation, paper, or record of study, and to make it accessible, in whole or in part, in all forms of media, now or hereafter known. Theses and Dissertations AUC Knowledge Fountain Watermelon Peel PVA Nanofibers |
| spellingShingle | Watermelon Peel PVA Nanofibers Soliman, Wafaa Fabrication of electrospun nanofibers made of watermelon peel extract and PVA and investigating their antioxidant and antibacterial activities |
| title | Fabrication of electrospun nanofibers made of watermelon peel extract and PVA and investigating their antioxidant and antibacterial activities |
| title_full | Fabrication of electrospun nanofibers made of watermelon peel extract and PVA and investigating their antioxidant and antibacterial activities |
| title_fullStr | Fabrication of electrospun nanofibers made of watermelon peel extract and PVA and investigating their antioxidant and antibacterial activities |
| title_full_unstemmed | Fabrication of electrospun nanofibers made of watermelon peel extract and PVA and investigating their antioxidant and antibacterial activities |
| title_short | Fabrication of electrospun nanofibers made of watermelon peel extract and PVA and investigating their antioxidant and antibacterial activities |
| title_sort | fabrication of electrospun nanofibers made of watermelon peel extract and pva and investigating their antioxidant and antibacterial activities |
| topic | Watermelon Peel PVA Nanofibers |
| url | https://fount.aucegypt.edu/etds/1562 https://fount.aucegypt.edu/context/etds/article/2597/viewcontent/Thesis_20final.pdf |
| work_keys_str_mv | AT solimanwafaa fabricationofelectrospunnanofibersmadeofwatermelonpeelextractandpvaandinvestigatingtheirantioxidantandantibacterialactivities |