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Impact of Intracellular Glutathione Depletion on Neutral Sphingomyelinase in Human Hepatoma HepG2 cells

Introduction: Incidence of hepatocellular carcinoma (HCC) has been increasing dramaticallyandliver cancer is the fifth most common cancer globally. Increasing sphingomyelin (SM) hydrolysis via activation of the cell surface membrane-associated neutral sphingomyelinase (nSMase) has been linked to cel...

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Bibliographic Details
Main Author: Tanios, Marie
Format: Thesis
Published: AUC Knowledge Fountain 2021
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