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Selective GSK3β inhibition mediates an Nrf2-independent anti-inflammatory microglial response
Glycogen Synthase Kinase 3 (GSK3) is associated with the proinflammatory phenotype of microglia and has been shown to act in concert with Nuclear factor kappa B (NF-κB). . GSK3 is also a suppressor of Nuclear factor erythroid 2-related factor 2 (Nrf2), the principal regulator of redox homeostasis. A...
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AUC Knowledge Fountain
2022
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