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Discovery of BMI-Associated Gut Microbiome Signatures in the AWI-Gen 2 Cohort

Obesity is increasing across sub-Saharan Africa amid rapid dietary, environmental, and urbanization transitions, yet the gut microbiome features associated with adiposity in African populations remain under-characterized. This study investigated whether species-level gut microbiome composition is as...

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Main Author: Yagoubi, Meriem
Format: Thesis
Published: AUC Knowledge Fountain 2026
Subjects:
gut microbiome
Body Mass Index (BMI)
AWI-Gen 2 cohort
African populations
MetaPhlAn taxonomic profiling
Machine learning
SHAP feature importance
Differential abundance analysis
Geographic microbiome variation
Compositional data analysis
Bioinformatics
Biotechnology
Environmental Microbiology and Microbial Ecology
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https://fount.aucegypt.edu/etds/2818
https://fount.aucegypt.edu/context/etds/article/3879/viewcontent/Final_Thesis___Meriem_Yagoubi.pdf

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