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Low risk of SARS-CoV-2 in blood transfusion
This article is published by Plos One and is also available at https://doi.org/10.1371/journal.pone.0249069
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| Format: | Article |
| Language: | English |
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PLOS ONE
2023
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| _version_ | 1869483596492832768 |
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| access_status_str | Open Access |
| author | Owusu Michael Sylverken Angelina Augustina El-Duah Philip Owusu-Dabo Ellis Amuasi John Adu Eric...et al |
| author_browse | Adu Eric...et al Amuasi John El-Duah Philip Owusu Michael Owusu-Dabo Ellis Sylverken Angelina Augustina |
| author_facet | Owusu Michael Sylverken Angelina Augustina El-Duah Philip Owusu-Dabo Ellis Amuasi John Adu Eric...et al |
| author_sort | Owusu Michael |
| collection | Thesis |
| description | This article is published by Plos One and is also available at https://doi.org/10.1371/journal.pone.0249069 |
| format | Article |
| id | oai:ir.knust.edu.gh:123456789/14731 |
| institution | KNUST (Ghana) |
| language | English |
| last_indexed | 2026-07-01T04:01:30.917Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana) |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | PLOS ONE |
| publisherStr | PLOS ONE |
| record_format | dspace |
| source_str | KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana) |
| spelling | oai:ir.knust.edu.gh:123456789/14731 Low risk of SARS-CoV-2 in blood transfusion Owusu Michael Sylverken Angelina Augustina El-Duah Philip Owusu-Dabo Ellis Amuasi John Adu Eric...et al This article is published by Plos One and is also available at https://doi.org/10.1371/journal.pone.0249069 The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), continues to remain a global challenge. There is emerging evidence of SARS-CoV-2 virus found in the blood of patients from China and some developed countries. However, there is inadequate data reported in Ghana and other parts of Africa, where blood transfusion service heavily relies on voluntary and replacement blood donors. This study aimed to investigate whether plasma of infected individuals could pose significant transfusion transmitted risk of COVID-19 in Ghanaian populations. Methods This cross-sectional retrospective study was conducted at the Kumasi Centre for Collabora tive Research into Tropical Medicine (KCCR), KNUST, Ghana. Study subjects comprised contacts of COVID-19 individuals, those with classical symptoms of COVID-19 and individu als who had recovered based on the new Ghana discharge criteria. Whole blood, sputum or deep coughed saliva samples were collected and transported to KCCR for SARS-CoV-2 testing. Viral nucleic acid was extracted from sputum/ nasopharyngeal samples using Da An Gene column based kit and from plasma using LBP nucleic acid extraction kit. Real-Time PCR was performed specifically targeting the ORF1ab and Nucleocapsid (N) genomic regions of the virus. Results A total of 97 individuals were recruited into the study, with more than half being males (58; 59.7%). The mean age of all subjects was 33 years (SD = 7.7) with minimum being 22 yearS KNUST 2023-12-11T09:50:13Z 2023-12-11T09:50:13Z 2021 Article Owusu M, Sylverken AA, El-Duah P, Ayisi Boateng NK, Yeboah R, Adu E, et al. (2021) Low risk of SARS-CoV-2 in blood transfusion. PLoS ONE 16(4): e0249069 10.1371/ journal.pone.0249069 https://ir.knust.edu.gh/handle/123456789/14731 en application/pdf PLOS ONE |
| spellingShingle | Owusu Michael Sylverken Angelina Augustina El-Duah Philip Owusu-Dabo Ellis Amuasi John Adu Eric...et al Low risk of SARS-CoV-2 in blood transfusion |
| title | Low risk of SARS-CoV-2 in blood transfusion |
| title_full | Low risk of SARS-CoV-2 in blood transfusion |
| title_fullStr | Low risk of SARS-CoV-2 in blood transfusion |
| title_full_unstemmed | Low risk of SARS-CoV-2 in blood transfusion |
| title_short | Low risk of SARS-CoV-2 in blood transfusion |
| title_sort | low risk of sars cov 2 in blood transfusion |
| url | https://ir.knust.edu.gh/handle/123456789/14731 |
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