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Phenolic Content, Antioxidant Properties and Antimicrobial Activities of the Extracts from Funtumia africana and Funtumia elastica

This article is published by Springer and is also available at https://doi.org/10.1007/s42250-021-00249-5

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Main Authors: Frempong Fadjare Theophilus, Badu Mercy, Boamah Etsiapa Vivian, Amponsah Kingsley Isaac...et al
Format: Article
Language:English
Published: Springer 2023
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access_status_str Open Access
author Frempong Fadjare Theophilus
Badu Mercy
Boamah Etsiapa Vivian
Amponsah Kingsley Isaac...et al
author_browse Amponsah Kingsley Isaac...et al
Badu Mercy
Boamah Etsiapa Vivian
Frempong Fadjare Theophilus
author_facet Frempong Fadjare Theophilus
Badu Mercy
Boamah Etsiapa Vivian
Amponsah Kingsley Isaac...et al
author_sort Frempong Fadjare Theophilus
collection Thesis
description This article is published by Springer and is also available at https://doi.org/10.1007/s42250-021-00249-5
format Article
id oai:ir.knust.edu.gh:123456789/14809
institution KNUST (Ghana)
language English
last_indexed 2026-07-01T04:00:53.925Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana)
publishDate 2023
publishDateRange 2023
publishDateSort 2023
publisher Springer
publisherStr Springer
record_format dspace
source_str KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana)
spelling oai:ir.knust.edu.gh:123456789/14809 Phenolic Content, Antioxidant Properties and Antimicrobial Activities of the Extracts from Funtumia africana and Funtumia elastica Frempong Fadjare Theophilus Badu Mercy Boamah Etsiapa Vivian Amponsah Kingsley Isaac...et al This article is published by Springer and is also available at https://doi.org/10.1007/s42250-021-00249-5 Funtumia africana and Funtumia elastica belong to a group of invaluable plants used in managing a wide range of diseases in West Africa. This study aimed at assessing the antioxidant and antimicrobial activities of extracts of the stem bark of F. africana and F. elastica. The dried, milled stem barks of F. africana and F. elastica were extracted with water and 70% ethanol by cold maceration. Total antioxidant capacity (TAC), total phenolic content (TPC), total flavonoids, and tannins were determined using standard methods. The extracts were tested against bacterial and fungal pathogens, namely; Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, and Candida albicans. The zone of inhibition, minimum inhibitory concentration (MIC), activity index, and the total antimicrobial activity of the extracts on the organisms were evaluated. Preliminary phytochemical screening revealed the presence of flavonoids, reducing sugars, anthocyanins, terpenoids, cardiac glycosides, quinones, tannins, and saponins. The ethanolic extract of F. elastica had the highest phenolic flavonoid contents and total antioxidant capacity. A positive correlation was observed between TPC with TAC (R = 0.893, p < 0.05) and TFC with TAC (R = 0.613, p < 0.05). The extracts were most active against E. coli and C. albicans and least active against B. subtilis and P. aeruginosa. The data obtained from the study indicated that the barks of the two plants possessed both antioxidant and antimicrobial properties. KNUST 2023-12-12T16:21:34Z 2023-12-12T16:21:34Z 2021 Article Chemistry Africa (2021) 4:503–512 https://doi.org/10.1007/s42250-021-00249-5 10.1007/s42250-021-00249-5 https://ir.knust.edu.gh/handle/123456789/14809 en application/pdf Springer
spellingShingle Frempong Fadjare Theophilus
Badu Mercy
Boamah Etsiapa Vivian
Amponsah Kingsley Isaac...et al
Phenolic Content, Antioxidant Properties and Antimicrobial Activities of the Extracts from Funtumia africana and Funtumia elastica
title Phenolic Content, Antioxidant Properties and Antimicrobial Activities of the Extracts from Funtumia africana and Funtumia elastica
title_full Phenolic Content, Antioxidant Properties and Antimicrobial Activities of the Extracts from Funtumia africana and Funtumia elastica
title_fullStr Phenolic Content, Antioxidant Properties and Antimicrobial Activities of the Extracts from Funtumia africana and Funtumia elastica
title_full_unstemmed Phenolic Content, Antioxidant Properties and Antimicrobial Activities of the Extracts from Funtumia africana and Funtumia elastica
title_short Phenolic Content, Antioxidant Properties and Antimicrobial Activities of the Extracts from Funtumia africana and Funtumia elastica
title_sort phenolic content antioxidant properties and antimicrobial activities of the extracts from funtumia africana and funtumia elastica
url https://ir.knust.edu.gh/handle/123456789/14809
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AT badumercy phenoliccontentantioxidantpropertiesandantimicrobialactivitiesoftheextractsfromfuntumiaafricanaandfuntumiaelastica
AT boamahetsiapavivian phenoliccontentantioxidantpropertiesandantimicrobialactivitiesoftheextractsfromfuntumiaafricanaandfuntumiaelastica
AT amponsahkingsleyisaacetal phenoliccontentantioxidantpropertiesandantimicrobialactivitiesoftheextractsfromfuntumiaafricanaandfuntumiaelastica