Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Pathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural Ghana: a case–control study
This article is published by Springer Nature and is also available at https://doi.org/10.1038/s41598-023-29410-5
Saved in:
| Main Authors: | , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2023
|
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1869483558067765248 |
|---|---|
| access_status_str | Open Access |
| author | Krumkamp Ralf Kohsar Matin Owusu-Dabo Ellis Nolte Kolja...et al |
| author2 | 0000-0003-4232-4292 |
| author_browse | 0000-0003-4232-4292 Kohsar Matin Krumkamp Ralf Nolte Kolja...et al Owusu-Dabo Ellis |
| author_facet | 0000-0003-4232-4292 Krumkamp Ralf Kohsar Matin Owusu-Dabo Ellis Nolte Kolja...et al |
| author_sort | Krumkamp Ralf |
| collection | Thesis |
| description | This article is published by Springer Nature and is also available at https://doi.org/10.1038/s41598-023-29410-5 |
| format | Article |
| id | oai:ir.knust.edu.gh:123456789/14834 |
| institution | KNUST (Ghana) |
| language | English |
| last_indexed | 2026-07-01T04:00:54.272Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana) |
| publishDate | 2023 |
| publishDateRange | 2023 |
| publishDateSort | 2023 |
| publisher | Springer Nature |
| publisherStr | Springer Nature |
| record_format | dspace |
| source_str | KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana) |
| spelling | oai:ir.knust.edu.gh:123456789/14834 Pathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural Ghana: a case–control study Krumkamp Ralf Kohsar Matin Owusu-Dabo Ellis Nolte Kolja...et al 0000-0003-4232-4292 This article is published by Springer Nature and is also available at https://doi.org/10.1038/s41598-023-29410-5 Respiratory infections are one of the most common causes of death among children under the age of five years. Data on prevalence and relevance of specific organisms in African children are still lacking. This case–control-study investigated prevalence and relevance of specific organisms in Ghanaian children admitted to hospital with symptoms of lower respiratory tract infection (LRTI). Pharyngeal swabs were taken and tested by PCR for 19 respiratory isolates. Adjusted odds ratios (aORs) were calculated to estimate associations between isolates and admission with LRTI. Population attributable fractions (PAFs) were calculated to assess the proportion of LRTI cases due to a particular pathogen. The study included 327 cases and 562 controls. We found associations between detection and admission for LRTI for influenza (aOR 98.6; 95% confidence interval (CI) 20.0–1789.6), respiratory syncytial virus (aOR 40.2; 95% CI 7.2–758.6), H. influenzae (aOR 4.1; 95% CI 2.2–7.9) and S. pneumoniae (aOR 2.4; 95% CI 1.7–3.4). PAFs ≥ 10% were observed for S. pneumoniae (30%; 95% CI 26–42), H. influenzae (10%; 95% CI 2–19) and influenza (10%; 95% CI 2–18). This study highlights the need for heightened surveillance and development of effective vaccines for respiratory pathogens other than SARS-CoV-2 in the future. KNUST 2023-12-13T15:26:24Z 2023-12-13T15:26:24Z 2023 Article Krumkamp, R., Kohsar, M., Nolte, K. et al. Pathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural Ghana: a case–control study. Sci Rep 13, 2443 (2023). https://doi.org/10.1038/s41598-023-29410-5 10.1038/s41598-023-29410-5 https://ir.knust.edu.gh/handle/123456789/14834 en application/pdf Springer Nature |
| spellingShingle | Krumkamp Ralf Kohsar Matin Owusu-Dabo Ellis Nolte Kolja...et al Pathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural Ghana: a case–control study |
| title | Pathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural Ghana: a case–control study |
| title_full | Pathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural Ghana: a case–control study |
| title_fullStr | Pathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural Ghana: a case–control study |
| title_full_unstemmed | Pathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural Ghana: a case–control study |
| title_short | Pathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural Ghana: a case–control study |
| title_sort | pathogens associated with hospitalization due to acute lower respiratory tract infections in children in rural ghana a case control study |
| url | https://ir.knust.edu.gh/handle/123456789/14834 |
| work_keys_str_mv | AT krumkampralf pathogensassociatedwithhospitalizationduetoacutelowerrespiratorytractinfectionsinchildreninruralghanaacasecontrolstudy AT kohsarmatin pathogensassociatedwithhospitalizationduetoacutelowerrespiratorytractinfectionsinchildreninruralghanaacasecontrolstudy AT owusudaboellis pathogensassociatedwithhospitalizationduetoacutelowerrespiratorytractinfectionsinchildreninruralghanaacasecontrolstudy AT noltekoljaetal pathogensassociatedwithhospitalizationduetoacutelowerrespiratorytractinfectionsinchildreninruralghanaacasecontrolstudy |