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Infl uenza outbreak among students in Ghana: a report from three time points
This is an article published in Research Gate on 17th September, 2020; Research Gate Publication on 17th September, 2020; https://doi.org/10.21203/rs.3.rs-34837/v3
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| Language: | English |
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Research Gate Publication
2024
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| _version_ | 1869483605065990144 |
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| access_status_str | Open Access |
| author | Sylverken, Augustina Angelina Owusu, Michael Yeboah, Richmond El-Duah, Philip Gorman, Richmond Bonney, Joseph Kofi Aryeetey, Sherihane Adu, Kofi et. al.. |
| author2 | 0000-0002-7691-914X |
| author_browse | 0000-0002-7691-914X Adu, Kofi Aryeetey, Sherihane Bonney, Joseph Kofi El-Duah, Philip Gorman, Richmond Owusu, Michael Sylverken, Augustina Angelina Yeboah, Richmond et. al.. |
| author_facet | 0000-0002-7691-914X Sylverken, Augustina Angelina Owusu, Michael Yeboah, Richmond El-Duah, Philip Gorman, Richmond Bonney, Joseph Kofi Aryeetey, Sherihane Adu, Kofi et. al.. |
| author_sort | Sylverken, Augustina Angelina |
| collection | Thesis |
| description | This is an article published in Research Gate on 17th September, 2020; Research Gate Publication on 17th September, 2020; https://doi.org/10.21203/rs.3.rs-34837/v3 |
| format | Article |
| id | oai:ir.knust.edu.gh:123456789/15509 |
| institution | KNUST (Ghana) |
| language | English |
| last_indexed | 2026-07-01T04:01:39.094Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana) |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Research Gate Publication |
| publisherStr | Research Gate Publication |
| record_format | dspace |
| source_str | KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana) |
| spelling | oai:ir.knust.edu.gh:123456789/15509 Infl uenza outbreak among students in Ghana: a report from three time points Sylverken, Augustina Angelina Owusu, Michael Yeboah, Richmond El-Duah, Philip Gorman, Richmond Bonney, Joseph Kofi Aryeetey, Sherihane Adu, Kofi et. al.. 0000-0002-7691-914X 0000-0001-5066-150X 0000-0002-2765-6179 0000-0003-1671-0755 0000-0002-6831-3375 This is an article published in Research Gate on 17th September, 2020; Research Gate Publication on 17th September, 2020; https://doi.org/10.21203/rs.3.rs-34837/v3 Background: Influenza viruses are known to be responsible for a number of respiratory disease outbreaks worldwide. While there exists documented information on influenza which allows for effective strategic preparedness activities in industrialized countries, the same cannot be said of developing and underdeveloped countries. It therefore behoves on developing countries to document information on circulating strains of influenza. Such information will enable prioritization of prevention and more targeted preparedness strategies. In this paper, we report on three different outbreaks of Influenza A among Ghanaian students in December 2017, May 2019 and December 2019 in the Ashanti region of Ghana. Methods: Throat or nasal samples were collected from all students who presented with signs and symptoms of fl u with flocked swabs, stored in RNAlater and transported to the laboratories of Kumasi Centre for Collaborative Research (KCCR) at ambient temperature. Following viral RNA extraction, detection of viral nucleic acid of both influenza A and its subtypes including H1N1 and H3N2 was done by real-time reverse transcription Polymerase Chain Reaction (RT-PCR). Results: A total of 112 samples were taken. An overall Influenza A prevalence of 51.8% (95% CI = 42.1-61.3) was recorded during the three outbreak time points. Of these, 11 (19.0%) were confirmed to be H1N1 (pdm09) and 47 (81.0%) were H3N2 strains. All the 11 H1N1 (pdm09) were identified during the first outbreak. The H3N2 strains were identified during the second and third outbreaks in May 2019 and December 2019 respectively. Our results show that influenza A virus activity was higher during the months of November and December compared to May. Age, contact with infected subjects, temperature, fever within the last 24 hours and headaches showed signifi cant variations (p-value <0.01) with respect to influenza A. Wald’s test revealed that subjects presenting with headaches had about 5 times odds (95%CI = 1.4-17.7) for infl enza A infection compared to subjects without headache (p = 0.014). Conclusion: Our study provides epidemiological information to better understand the incidence and burden of influenza to allow for prioritisation of prevention and control strategies. Such information would aid in controlling and preparing for future influenza epidemics. KNUST 2024-02-21T10:33:09Z 2024-02-21T10:33:09Z 2020-09-17 Article Research Gate Publication on 17th September, 2020; https://doi.org/10.21203/rs.3.rs-34837/v3 https://ir.knust.edu.gh/handle/123456789/15509 en application/pdf Research Gate Publication |
| spellingShingle | Sylverken, Augustina Angelina Owusu, Michael Yeboah, Richmond El-Duah, Philip Gorman, Richmond Bonney, Joseph Kofi Aryeetey, Sherihane Adu, Kofi et. al.. Infl uenza outbreak among students in Ghana: a report from three time points |
| title | Infl uenza outbreak among students in Ghana: a report from three time points |
| title_full | Infl uenza outbreak among students in Ghana: a report from three time points |
| title_fullStr | Infl uenza outbreak among students in Ghana: a report from three time points |
| title_full_unstemmed | Infl uenza outbreak among students in Ghana: a report from three time points |
| title_short | Infl uenza outbreak among students in Ghana: a report from three time points |
| title_sort | infl uenza outbreak among students in ghana a report from three time points |
| url | https://ir.knust.edu.gh/handle/123456789/15509 |
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