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Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in Ghana

This is an article published in Ghana Med J 2020; 54(4) supplement: 39-45; doi: http://dx.doi.org/10.4314/gmj.v54i4s.7

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Main Authors: Ayisi-Boateng Nana Kwame, Owusu, Michael, Tawiah, Phyllis, Ampah, Brenda A., Sylverken, Augustina Angelina, Wusu-Ansah, Owusu K., Sarfo, Fred S., Phillips, Richard Odame
Other Authors: 0000-0002-0961-4434
Format: Article
Language:English
Published: Ghana Med J. 2024
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access_status_str Open Access
author Ayisi-Boateng Nana Kwame
Owusu, Michael
Tawiah, Phyllis
Ampah, Brenda A.
Sylverken, Augustina Angelina
Wusu-Ansah, Owusu K.
Sarfo, Fred S.
Phillips, Richard Odame,
author2 0000-0002-0961-4434
author_browse 0000-0002-0961-4434
Ampah, Brenda A.
Ayisi-Boateng Nana Kwame
Owusu, Michael
Phillips, Richard Odame,
Sarfo, Fred S.
Sylverken, Augustina Angelina
Tawiah, Phyllis
Wusu-Ansah, Owusu K.
author_facet 0000-0002-0961-4434
Ayisi-Boateng Nana Kwame
Owusu, Michael
Tawiah, Phyllis
Ampah, Brenda A.
Sylverken, Augustina Angelina
Wusu-Ansah, Owusu K.
Sarfo, Fred S.
Phillips, Richard Odame,
author_sort Ayisi-Boateng Nana Kwame
collection Thesis
description This is an article published in Ghana Med J 2020; 54(4) supplement: 39-45; doi: http://dx.doi.org/10.4314/gmj.v54i4s.7
format Article
id oai:ir.knust.edu.gh:123456789/15521
institution KNUST (Ghana)
language English
last_indexed 2026-06-10T12:31:22.621Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana)
publishDate 2024
publishDateRange 2024
publishDateSort 2024
publisher Ghana Med J.
publisherStr Ghana Med J.
record_format dspace
source_str KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana)
spelling oai:ir.knust.edu.gh:123456789/15521 Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in Ghana Ayisi-Boateng Nana Kwame Owusu, Michael Tawiah, Phyllis Ampah, Brenda A. Sylverken, Augustina Angelina Wusu-Ansah, Owusu K. Sarfo, Fred S. Phillips, Richard Odame, 0000-0002-0961-4434 0000-0001-5066-150X 0000-0002-2641-8865 0000-0003-0588-0337 This is an article published in Ghana Med J 2020; 54(4) supplement: 39-45; doi: http://dx.doi.org/10.4314/gmj.v54i4s.7 Background: In high-income countries, mortality related to hospitalized patients with the Coronavirus disease 2019 (COVID-19) is approximately 4-5%. However, data on COVID-19 admissions from sub-Saharan Africa are scanty. Objective: To describe the clinical profile and determinants of outcomes of patients with confirmed COVID-19 admitted at a hospital in Ghana. Methods: A prospective study involving 25 patients with real time polymerase chain reaction confirmed COVID-19 admitted to the treatment centre of the University Hospital, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana from 1st June to 27th July, 2020. They were managed and followed up for outcomes. Data were analysed descriptively, and predictors of mortality assessed using a multivariate logistic regression modelling. Results: The mean age of the patients was 59.3 ± 20.6 years, and 14 (56%) were males. The main symptoms at presentation were breathlessness (68%) followed by fever (56%). The cases were categorized as mild (6), moderate (6), severe (10) and critical (3). Hypertension was the commonest comorbidity present in 72% of patients. Medications used in patient management included dexamethasone (68%), azithromycin (96%), and hydroxychloroquine (4%). Five of 25 cases died (Case fatality ratio 20%). Increasing age and high systolic blood pressure were associated with mortality. Conclusion: Case fatality in this sample of hospitalized COVID-19 patients was high. Thorough clinical assessment, severity stratification, aggressive management of underlying co-morbidities and standardized protocols in country might improve outcomes. KNUST 2024-02-21T11:57:09Z 2024-02-21T11:57:09Z 2020 Article Ghana Med J 2020; 54(4) supplement: 39-45 doi: http://dx.doi.org/10.4314/gmj.v54i4s.7 http://dx.doi.org/10.4314/gmj.v54i4s.7 https://ir.knust.edu.gh/handle/123456789/15521 en application/pdf Ghana Med J.
spellingShingle Ayisi-Boateng Nana Kwame
Owusu, Michael
Tawiah, Phyllis
Ampah, Brenda A.
Sylverken, Augustina Angelina
Wusu-Ansah, Owusu K.
Sarfo, Fred S.
Phillips, Richard Odame,
Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in Ghana
title Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in Ghana
title_full Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in Ghana
title_fullStr Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in Ghana
title_full_unstemmed Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in Ghana
title_short Profile and outcomes of hospitalized patients with COVID-19 at a tertiary institution hospital in Ghana
title_sort profile and outcomes of hospitalized patients with covid 19 at a tertiary institution hospital in ghana
url http://dx.doi.org/10.4314/gmj.v54i4s.7
https://ir.knust.edu.gh/handle/123456789/15521
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