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Radiation Therapy for Breast Cancer in Africa

This article is published by Elseviere, 2023 and is also available at https://doi.org/10.1016/j.adro.2024.101488

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Main Authors: Oppong, Rita, Yeboah, David, Owusu-Ansah, Mohammed, Salifu, Samson Pandam
Other Authors: 0000-0003-2092-6452
Format: Article
Language:English
Published: Elsevier 2024
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access_status_str Open Access
author Oppong, Rita
Yeboah, David
Owusu-Ansah, Mohammed
Salifu, Samson Pandam
author2 0000-0003-2092-6452
author_browse 0000-0003-2092-6452
Oppong, Rita
Owusu-Ansah, Mohammed
Salifu, Samson Pandam
Yeboah, David
author_facet 0000-0003-2092-6452
Oppong, Rita
Yeboah, David
Owusu-Ansah, Mohammed
Salifu, Samson Pandam
author_sort Oppong, Rita
collection Thesis
description This article is published by Elseviere, 2023 and is also available at https://doi.org/10.1016/j.adro.2024.101488
format Article
id oai:ir.knust.edu.gh:123456789/15868
institution KNUST (Ghana)
language English
last_indexed 2026-07-01T04:01:44.211Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana)
publishDate 2024
publishDateRange 2024
publishDateSort 2024
publisher Elsevier
publisherStr Elsevier
record_format dspace
source_str KNUSTSpace — Kwame Nkrumah University of Science & Technology (Ghana)
spelling oai:ir.knust.edu.gh:123456789/15868 Radiation Therapy for Breast Cancer in Africa Oppong, Rita Yeboah, David Owusu-Ansah, Mohammed Salifu, Samson Pandam 0000-0003-2092-6452 This article is published by Elseviere, 2023 and is also available at https://doi.org/10.1016/j.adro.2024.101488 Purpose: Although radiation therapy is an effective treatment for breast cancer, it has a low rate of use in African countries. A systematic review was undertaken to investigate studies that used radiation therapy as a treatment modality for patients with breast cancer in Africa, focusing on survival outcomes, adverse effects, radiation therapy techniques, fractionation schedules, and effectiveness of radiation therapy. Methods and Materials: We conducted a comprehensive literature search for studies that treated breast cancer with radiation therapy, using different electronic databases (PubMed, Scopus, and EBSCOhost) up to February 2023. The output was exported to a reference management system for analyses. Results: The literature search primarily identified 3804 records from Scopus (2427), PubMed (982), and EBSCOhost (395). Based on the inclusion and exclusion criteria, 19 articles were finally included in this systematic review. Most of the studies published were conducted in North Africa (63%), followed by West Africa (21%) and Southeast Africa (16%). Most centers employed external beam radiation therapy to deliver radiation therapy to patients with breast cancer with the standard fractionation size of 50 Gy in 25 fractions. The long-term outcomes with regards to adverse effect suggests that radiation therapy was fairly tolerated among patients with breast cancer. Conclusions: The reports provide substantial evidence that there are limited number of published studies on the use of radiation therapy for breast cancer treatment in Africa, as well as lower overall survival rate compared with developed countries. To improve breast cancer survivorship, it is necessary for government and other health care planners to provide more radiation therapy resources and implement training programs for personnels. KNUST 2024-07-24T09:05:01Z 2024-07-24T09:05:01Z 2024 Article Advances in Radiation Oncology (2024) 9, 101488 10.1016/j.adro.2024.101488 https://ir.knust.edu.gh/handle/123456789/15868 en application/pdf Elsevier
spellingShingle Oppong, Rita
Yeboah, David
Owusu-Ansah, Mohammed
Salifu, Samson Pandam
Radiation Therapy for Breast Cancer in Africa
title Radiation Therapy for Breast Cancer in Africa
title_full Radiation Therapy for Breast Cancer in Africa
title_fullStr Radiation Therapy for Breast Cancer in Africa
title_full_unstemmed Radiation Therapy for Breast Cancer in Africa
title_short Radiation Therapy for Breast Cancer in Africa
title_sort radiation therapy for breast cancer in africa
url https://ir.knust.edu.gh/handle/123456789/15868
work_keys_str_mv AT oppongrita radiationtherapyforbreastcancerinafrica
AT yeboahdavid radiationtherapyforbreastcancerinafrica
AT owusuansahmohammed radiationtherapyforbreastcancerinafrica
AT salifusamsonpandam radiationtherapyforbreastcancerinafrica