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Modelling and simulation based assessment in sustainable bioprocess development
Modelling and simulation enhance our insight and understanding of chemical processes and aid in identifying bottlenecks and potential improvements. A simplified simulation package, providing a reasonable estimate of material and energy usage and process emissions is often valuable in very early stag...
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Centre for Bioprocess Engineering Research
2014
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| _version_ | 1867613391979282433 |
|---|---|
| access_status_str | Open Access |
| author | De Beer, Adrian |
| author2 | Harrison, STL |
| author_browse | De Beer, Adrian Harrison, STL |
| author_facet | Harrison, STL De Beer, Adrian |
| author_sort | De Beer, Adrian |
| collection | Thesis |
| description | Modelling and simulation enhance our insight and understanding of chemical processes and aid in identifying bottlenecks and potential improvements. A simplified simulation package, providing a reasonable estimate of material and energy usage and process emissions is often valuable in very early stages of process development, when temporal and financial limitations do not allow for more detailed estimates. Environmental burdens are an increasing concern in industrial processes and various methodologies and tools have been developed for gathering and analysis of process information to enhance understanding of the process system and inform decision makers. The systems nature of these approaches is aimed at mitigation of environmental burdens through improved technologies, sustainable resource consumption and screening of process alternatives. Ideally, the process design team should bring together these tools in early stages of development when design flexibility is greatest. In the present study, such a simplified approach to bioprocess design is demonstrated using a case study for the large-scale production of citric acid. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/10365 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:35:24.907Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Centre for Bioprocess Engineering Research |
| publisherStr | Centre for Bioprocess Engineering Research |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/10365 Modelling and simulation based assessment in sustainable bioprocess development De Beer, Adrian Harrison, STL Bioprocess Engineering Modelling and simulation enhance our insight and understanding of chemical processes and aid in identifying bottlenecks and potential improvements. A simplified simulation package, providing a reasonable estimate of material and energy usage and process emissions is often valuable in very early stages of process development, when temporal and financial limitations do not allow for more detailed estimates. Environmental burdens are an increasing concern in industrial processes and various methodologies and tools have been developed for gathering and analysis of process information to enhance understanding of the process system and inform decision makers. The systems nature of these approaches is aimed at mitigation of environmental burdens through improved technologies, sustainable resource consumption and screening of process alternatives. Ideally, the process design team should bring together these tools in early stages of development when design flexibility is greatest. In the present study, such a simplified approach to bioprocess design is demonstrated using a case study for the large-scale production of citric acid. 2014-12-28T14:52:57Z 2014-12-28T14:52:57Z 2011 Master Thesis Masters MSc http://hdl.handle.net/11427/10365 eng application/pdf Centre for Bioprocess Engineering Research Faculty of Engineering and the Built Environment University of Cape Town |
| spellingShingle | Bioprocess Engineering De Beer, Adrian Modelling and simulation based assessment in sustainable bioprocess development |
| thesis_degree_str | Master's |
| title | Modelling and simulation based assessment in sustainable bioprocess development |
| title_full | Modelling and simulation based assessment in sustainable bioprocess development |
| title_fullStr | Modelling and simulation based assessment in sustainable bioprocess development |
| title_full_unstemmed | Modelling and simulation based assessment in sustainable bioprocess development |
| title_short | Modelling and simulation based assessment in sustainable bioprocess development |
| title_sort | modelling and simulation based assessment in sustainable bioprocess development |
| topic | Bioprocess Engineering |
| url | http://hdl.handle.net/11427/10365 |
| work_keys_str_mv | AT debeeradrian modellingandsimulationbasedassessmentinsustainablebioprocessdevelopment |