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Genetic factors associated with performance and exercise-associated weight loss in Ironman triathletes
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Human Biology
2014
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| _version_ | 1867614428989489152 |
|---|---|
| access_status_str | Open Access |
| author | De Milander, Liesl |
| author2 | Collins, Malcolm |
| author_browse | Collins, Malcolm De Milander, Liesl |
| author_facet | Collins, Malcolm De Milander, Liesl |
| author_sort | De Milander, Liesl |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/10372 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:51:53.876Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Human Biology |
| publisherStr | Department of Human Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/10372 Genetic factors associated with performance and exercise-associated weight loss in Ironman triathletes De Milander, Liesl Collins, Malcolm Human Biology Includes bibliographical references. The aim of this thesis was to investigate candidate genes, mainly within the CNS, that may contribute to the variation in physiological responses (body weight changes) and athletic ability between athletes during participation in a 226 km Ironman triathlon. A genetic association approach was used in case-control studies to identify specific sequence variants within selected candidate genes. These candidate genes (IL-6, 5-HTT and MAO-A) were selected based on the biological function of their encoded proteins, which have been implicated in peripheral and central fatigue models. Candidate genes (5-HTT and AVPR2) that encode for proteins that play key roles in the neuro-endocrine control of total body water homeostasis were also investigated in this thesis. 2014-12-28T14:54:32Z 2014-12-28T14:54:32Z 2012 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/10372 eng application/pdf Department of Human Biology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Human Biology De Milander, Liesl Genetic factors associated with performance and exercise-associated weight loss in Ironman triathletes |
| thesis_degree_str | Doctoral |
| title | Genetic factors associated with performance and exercise-associated weight loss in Ironman triathletes |
| title_full | Genetic factors associated with performance and exercise-associated weight loss in Ironman triathletes |
| title_fullStr | Genetic factors associated with performance and exercise-associated weight loss in Ironman triathletes |
| title_full_unstemmed | Genetic factors associated with performance and exercise-associated weight loss in Ironman triathletes |
| title_short | Genetic factors associated with performance and exercise-associated weight loss in Ironman triathletes |
| title_sort | genetic factors associated with performance and exercise associated weight loss in ironman triathletes |
| topic | Human Biology |
| url | http://hdl.handle.net/11427/10372 |
| work_keys_str_mv | AT demilanderliesl geneticfactorsassociatedwithperformanceandexerciseassociatedweightlossinironmantriathletes |