Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Investigations into the stability of growth factor induced-vasculature and the effects of synthetic biomaterials on heart remodelling after myocardial infarction
This work was based on the hypothesis that optimization of growth factor delivery rate and duration, combined with a biomaterial scaffold, could lead to an improved strategy for therapeutic neovascularization. To test this hypothesis, a novel in vivo model system that allows for characterization of...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Surgery
2014
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613252012212224 |
|---|---|
| access_status_str | Open Access |
| author | Dobner, Stephan |
| author2 | Davies, Neil |
| author_browse | Davies, Neil Dobner, Stephan |
| author_facet | Davies, Neil Dobner, Stephan |
| author_sort | Dobner, Stephan |
| collection | Thesis |
| description | This work was based on the hypothesis that optimization of growth factor delivery rate and duration, combined with a biomaterial scaffold, could lead to an improved strategy for therapeutic neovascularization. To test this hypothesis, a novel in vivo model system that allows for characterization of stability and mural cell investment of newly created vessels was designed. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/10386 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:33:10.259Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Surgery |
| publisherStr | Department of Surgery |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/10386 Investigations into the stability of growth factor induced-vasculature and the effects of synthetic biomaterials on heart remodelling after myocardial infarction Dobner, Stephan Davies, Neil Surgery This work was based on the hypothesis that optimization of growth factor delivery rate and duration, combined with a biomaterial scaffold, could lead to an improved strategy for therapeutic neovascularization. To test this hypothesis, a novel in vivo model system that allows for characterization of stability and mural cell investment of newly created vessels was designed. 2014-12-28T14:56:51Z 2014-12-28T14:56:51Z 2011 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/10386 eng application/pdf Department of Surgery Faculty of Health Sciences University of Cape Town |
| spellingShingle | Surgery Dobner, Stephan Investigations into the stability of growth factor induced-vasculature and the effects of synthetic biomaterials on heart remodelling after myocardial infarction |
| thesis_degree_str | Doctoral |
| title | Investigations into the stability of growth factor induced-vasculature and the effects of synthetic biomaterials on heart remodelling after myocardial infarction |
| title_full | Investigations into the stability of growth factor induced-vasculature and the effects of synthetic biomaterials on heart remodelling after myocardial infarction |
| title_fullStr | Investigations into the stability of growth factor induced-vasculature and the effects of synthetic biomaterials on heart remodelling after myocardial infarction |
| title_full_unstemmed | Investigations into the stability of growth factor induced-vasculature and the effects of synthetic biomaterials on heart remodelling after myocardial infarction |
| title_short | Investigations into the stability of growth factor induced-vasculature and the effects of synthetic biomaterials on heart remodelling after myocardial infarction |
| title_sort | investigations into the stability of growth factor induced vasculature and the effects of synthetic biomaterials on heart remodelling after myocardial infarction |
| topic | Surgery |
| url | http://hdl.handle.net/11427/10386 |
| work_keys_str_mv | AT dobnerstephan investigationsintothestabilityofgrowthfactorinducedvasculatureandtheeffectsofsyntheticbiomaterialsonheartremodellingaftermyocardialinfarction |