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Familial association of polycystic ovary syndrome (PCOS) in women attending the gynaecological endocrinology clinic at Groote Schuur Hospital

Includes bibliographical references (leaves 60-65).

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Main Author: Edelstein, Sascha
Other Authors: van der Spuy, Zephne Margaret
Format: Thesis
Language:English
Published: Department of Obstetrics and Gynaecology 2014
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access_status_str Open Access
author Edelstein, Sascha
author2 van der Spuy, Zephne Margaret
author_browse Edelstein, Sascha
van der Spuy, Zephne Margaret
author_facet van der Spuy, Zephne Margaret
Edelstein, Sascha
author_sort Edelstein, Sascha
collection Thesis
description Includes bibliographical references (leaves 60-65).
format Thesis
id oai:open.uct.ac.za:11427/10437
institution University of Cape Town (South Africa)
language eng
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2014
publishDateRange 2014
publishDateSort 2014
publisher Department of Obstetrics and Gynaecology
publisherStr Department of Obstetrics and Gynaecology
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/10437 Familial association of polycystic ovary syndrome (PCOS) in women attending the gynaecological endocrinology clinic at Groote Schuur Hospital Edelstein, Sascha van der Spuy, Zephne Margaret Reproductive Medicine Includes bibliographical references (leaves 60-65). Polycystic ovary syndrome (PCOS) is the commonest endocrinopathy in women of reproductive age, affecting 5-10% of women in the general population. Patients present with menstrual disturbances, infertility and clinical hyperandrogenism. While the pathophysiology is not completely delineated, a strong familial association has been demonstrated, suggesting a genetic component. From January 2007 until February 2009, a total of 83 probands were recruited from the Gynaecological Endocrinology Clinic (GEC) at GSH. These were all women with PCOS according to the Rotterdam criteria who presented for management at the GEC. With their consent, first degree female family members were contacted and 57 mothers, 108 sisters and 8 daughters agreed to participate in the study. 2014-12-28T20:07:16Z 2014-12-28T20:07:16Z 2010 Master Thesis Masters MPhil http://hdl.handle.net/11427/10437 eng application/pdf Department of Obstetrics and Gynaecology Faculty of Health Sciences University of Cape Town
spellingShingle Reproductive Medicine
Edelstein, Sascha
Familial association of polycystic ovary syndrome (PCOS) in women attending the gynaecological endocrinology clinic at Groote Schuur Hospital
thesis_degree_str Master's
title Familial association of polycystic ovary syndrome (PCOS) in women attending the gynaecological endocrinology clinic at Groote Schuur Hospital
title_full Familial association of polycystic ovary syndrome (PCOS) in women attending the gynaecological endocrinology clinic at Groote Schuur Hospital
title_fullStr Familial association of polycystic ovary syndrome (PCOS) in women attending the gynaecological endocrinology clinic at Groote Schuur Hospital
title_full_unstemmed Familial association of polycystic ovary syndrome (PCOS) in women attending the gynaecological endocrinology clinic at Groote Schuur Hospital
title_short Familial association of polycystic ovary syndrome (PCOS) in women attending the gynaecological endocrinology clinic at Groote Schuur Hospital
title_sort familial association of polycystic ovary syndrome pcos in women attending the gynaecological endocrinology clinic at groote schuur hospital
topic Reproductive Medicine
url http://hdl.handle.net/11427/10437
work_keys_str_mv AT edelsteinsascha familialassociationofpolycysticovarysyndromepcosinwomenattendingthegynaecologicalendocrinologyclinicatgrooteschuurhospital