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Construction, stability and immunogenicity of recombinant BCG expressing HIV-1 subtype C gag under the control of MtrA promoter, with or without the leader sequences
This study aimed to compare recombinant mycobacteria expressing HIV-1 gag under the control of different promoters and leader sequences. This was done to determine whether the genetic stability of the recombinant mycobacteria could be improved by modification of these vector features and to gain ins...
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Division of Virology
2014
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| _version_ | 1867611359067242496 |
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| access_status_str | Open Access |
| author | Lebeko, Maribanyana R |
| author2 | Chapman, Ros |
| author_browse | Chapman, Ros Lebeko, Maribanyana R |
| author_facet | Chapman, Ros Lebeko, Maribanyana R |
| author_sort | Lebeko, Maribanyana R |
| collection | Thesis |
| description | This study aimed to compare recombinant mycobacteria expressing HIV-1 gag under the control of different promoters and leader sequences. This was done to determine whether the genetic stability of the recombinant mycobacteria could be improved by modification of these vector features and to gain insight into what types of immune responses may be elicited in mice. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/10586 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Division of Virology |
| publisherStr | Division of Virology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/10586 Construction, stability and immunogenicity of recombinant BCG expressing HIV-1 subtype C gag under the control of MtrA promoter, with or without the leader sequences Lebeko, Maribanyana R Chapman, Ros Williamson, Anna-Lise Medical Virology This study aimed to compare recombinant mycobacteria expressing HIV-1 gag under the control of different promoters and leader sequences. This was done to determine whether the genetic stability of the recombinant mycobacteria could be improved by modification of these vector features and to gain insight into what types of immune responses may be elicited in mice. 2014-12-30T19:39:19Z 2014-12-30T19:39:19Z 2011 Master Thesis Masters MSc http://hdl.handle.net/11427/10586 eng application/pdf Division of Virology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medical Virology Lebeko, Maribanyana R Construction, stability and immunogenicity of recombinant BCG expressing HIV-1 subtype C gag under the control of MtrA promoter, with or without the leader sequences |
| thesis_degree_str | Master's |
| title | Construction, stability and immunogenicity of recombinant BCG expressing HIV-1 subtype C gag under the control of MtrA promoter, with or without the leader sequences |
| title_full | Construction, stability and immunogenicity of recombinant BCG expressing HIV-1 subtype C gag under the control of MtrA promoter, with or without the leader sequences |
| title_fullStr | Construction, stability and immunogenicity of recombinant BCG expressing HIV-1 subtype C gag under the control of MtrA promoter, with or without the leader sequences |
| title_full_unstemmed | Construction, stability and immunogenicity of recombinant BCG expressing HIV-1 subtype C gag under the control of MtrA promoter, with or without the leader sequences |
| title_short | Construction, stability and immunogenicity of recombinant BCG expressing HIV-1 subtype C gag under the control of MtrA promoter, with or without the leader sequences |
| title_sort | construction stability and immunogenicity of recombinant bcg expressing hiv 1 subtype c gag under the control of mtra promoter with or without the leader sequences |
| topic | Medical Virology |
| url | http://hdl.handle.net/11427/10586 |
| work_keys_str_mv | AT lebekomaribanyanar constructionstabilityandimmunogenicityofrecombinantbcgexpressinghiv1subtypecgagunderthecontrolofmtrapromoterwithorwithouttheleadersequences |