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Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome

Includes bibliography.

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Bibliographic Details
Main Author: Radebold, Klaus
Other Authors: Bornman, PC
Format: Thesis
Language:English
Published: Department of Surgery 2014
Subjects:
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access_status_str Open Access
author Radebold, Klaus
author2 Bornman, PC
author_browse Bornman, PC
Radebold, Klaus
author_facet Bornman, PC
Radebold, Klaus
author_sort Radebold, Klaus
collection Thesis
description Includes bibliography.
format Thesis
id oai:open.uct.ac.za:11427/10762
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:43:12.903Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2014
publishDateRange 2014
publishDateSort 2014
publisher Department of Surgery
publisherStr Department of Surgery
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/10762 Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome Radebold, Klaus Bornman, PC Surgery Includes bibliography. Despite major advances over the last two decades with the management of patients with Zollinger-Ellison syndrome (ZES), unanswered questions remain concerning the natural history of the disease, the impact of new diagnostics modalities on cure rates, and the role of surgery in the era of modem medical therapies. The aims of the thesis are to (i) analyse the database of 40 ZES patients treated at Groote Schuur Hospital (GSH) over two decades, with special reference to the impact of various surgical strategies on outcome, (ii) investigate a possible correlation between biological tissue marker expression and tumour behaviour, (iii) study the effect of somatostatin receptor scintigraphy (SRS) on surgical cure rates, and (iv) assess the efficacy and safety of a new proton pump inhibitor (pantoprazole) in controlling acid hypersecretion. 2014-12-31T19:54:34Z 2014-12-31T19:54:34Z 2000 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/10762 eng application/pdf Department of Surgery Faculty of Health Sciences University of Cape Town
spellingShingle Surgery
Radebold, Klaus
Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome
thesis_degree_str Doctoral
title Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome
title_full Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome
title_fullStr Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome
title_full_unstemmed Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome
title_short Evaluation of new diagnostic and treatment strategies in the management of the Zollinger-Ellison syndrome
title_sort evaluation of new diagnostic and treatment strategies in the management of the zollinger ellison syndrome
topic Surgery
url http://hdl.handle.net/11427/10762
work_keys_str_mv AT radeboldklaus evaluationofnewdiagnosticandtreatmentstrategiesinthemanagementofthezollingerellisonsyndrome