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The short-term effects of off-pump cardiopulmonary bypass graft surgery on cognitive performance
Includes bibliographical references (leaves 56-67).
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| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
Department of Psychology
2014
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| _version_ | 1867613181919100928 |
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| access_status_str | Open Access |
| author | Pursch, Lindsay Jane |
| author_browse | Pursch, Lindsay Jane |
| author_facet | Pursch, Lindsay Jane |
| author_sort | Pursch, Lindsay Jane |
| collection | Thesis |
| description | Includes bibliographical references (leaves 56-67). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/10772 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:03.909Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Psychology |
| publisherStr | Department of Psychology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/10772 The short-term effects of off-pump cardiopulmonary bypass graft surgery on cognitive performance Pursch, Lindsay Jane Psychological Research Includes bibliographical references (leaves 56-67). Postoperative neurocognitive impairment has been associated with coronary artery bypass graft surgery (CABG). This study investigates the short-term effects of off-pump cardiopulmonary bypass graft surgery (OPCAB) on cognitive performance, as a possible safer alternative in the treatment of coronary artery disease. This research forms part of a larger study in which, in addition to the OPCAB procedure, the cognitive effects of CABG surgery and percutaneous transluminal coronary angioplasty with intra-coronary stenting are assessed. 36 participants undergoing OPCAB surgery were included in the study, with a further 36 participants included as an age- and education- matched non-surgical control group. A standardized battery of neuropsychological tests, designed to assess seven cognitive domains, was administered on two occasions, preoperatively at 1-2 days prior to surgery, and postoperatively at 1 month after surgery, with control participant assessments at the same intervals. Emotional state scales assessing depression and anxiety levels were administered at each assessment. Data analysis included a two-way mixed analysis of variance conducted on each measure of cognitive function, and on the indicators of emotional state. In addition, standard multiple regression was conducted to assess whether change in emotional state is able to predict change in any of the cognitive domains. Results indicated no evidence of short-term cognitive decline, and highlighted an improvement in cognitive performance in both surgical and control groups in the domain of language, psychomotor speed, executive function and visual memory, with the control group demonstrating a consistently superior performance. This counter-intuitive finding could not be attributed to practice effects. 2014-12-31T19:56:24Z 2014-12-31T19:56:24Z 2008 Master Thesis Masters MA http://hdl.handle.net/11427/10772 eng application/pdf Department of Psychology Faculty of Humanities University of Cape Town |
| spellingShingle | Psychological Research Pursch, Lindsay Jane The short-term effects of off-pump cardiopulmonary bypass graft surgery on cognitive performance |
| thesis_degree_str | Master's |
| title | The short-term effects of off-pump cardiopulmonary bypass graft surgery on cognitive performance |
| title_full | The short-term effects of off-pump cardiopulmonary bypass graft surgery on cognitive performance |
| title_fullStr | The short-term effects of off-pump cardiopulmonary bypass graft surgery on cognitive performance |
| title_full_unstemmed | The short-term effects of off-pump cardiopulmonary bypass graft surgery on cognitive performance |
| title_short | The short-term effects of off-pump cardiopulmonary bypass graft surgery on cognitive performance |
| title_sort | short term effects of off pump cardiopulmonary bypass graft surgery on cognitive performance |
| topic | Psychological Research |
| url | http://hdl.handle.net/11427/10772 |
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