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A pathway-based approach investigating DNA sequence variants to implicate the inflammatory pathway in the predisposition to Achilles tendinopathy
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
MRC/UCT RU for Exercise and Sport Medicine
2015
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| _version_ | 1867613187525836800 |
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| access_status_str | Open Access |
| author | Nell, Erica-Mari |
| author2 | September, Alison |
| author_browse | Nell, Erica-Mari September, Alison |
| author_facet | September, Alison Nell, Erica-Mari |
| author_sort | Nell, Erica-Mari |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/10807 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:09.918Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | MRC/UCT RU for Exercise and Sport Medicine |
| publisherStr | MRC/UCT RU for Exercise and Sport Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/10807 A pathway-based approach investigating DNA sequence variants to implicate the inflammatory pathway in the predisposition to Achilles tendinopathy Nell, Erica-Mari September, Alison Physiology Includes abstract. Includes bibliographical references (leaves 159-179). The aims of this dissertation were therefore (i) to follow a pathway-based approach investigating genes encoding proteins involved in the ECM degradation and apoptosis signalling cascade for associations with AT and (ii) to identify a polygenic risk model, comprised of several genetic markers within genes encoding proteins involved in the inflammatory pathway, to predict risk of AT. 2015-01-01T12:16:26Z 2015-01-01T12:16:26Z 2011 Master Thesis Masters MSc http://hdl.handle.net/11427/10807 eng application/pdf MRC/UCT RU for Exercise and Sport Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Physiology Nell, Erica-Mari A pathway-based approach investigating DNA sequence variants to implicate the inflammatory pathway in the predisposition to Achilles tendinopathy |
| thesis_degree_str | Master's |
| title | A pathway-based approach investigating DNA sequence variants to implicate the inflammatory pathway in the predisposition to Achilles tendinopathy |
| title_full | A pathway-based approach investigating DNA sequence variants to implicate the inflammatory pathway in the predisposition to Achilles tendinopathy |
| title_fullStr | A pathway-based approach investigating DNA sequence variants to implicate the inflammatory pathway in the predisposition to Achilles tendinopathy |
| title_full_unstemmed | A pathway-based approach investigating DNA sequence variants to implicate the inflammatory pathway in the predisposition to Achilles tendinopathy |
| title_short | A pathway-based approach investigating DNA sequence variants to implicate the inflammatory pathway in the predisposition to Achilles tendinopathy |
| title_sort | pathway based approach investigating dna sequence variants to implicate the inflammatory pathway in the predisposition to achilles tendinopathy |
| topic | Physiology |
| url | http://hdl.handle.net/11427/10807 |
| work_keys_str_mv | AT nellericamari apathwaybasedapproachinvestigatingdnasequencevariantstoimplicatetheinflammatorypathwayinthepredispositiontoachillestendinopathy AT nellericamari pathwaybasedapproachinvestigatingdnasequencevariantstoimplicatetheinflammatorypathwayinthepredispositiontoachillestendinopathy |