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The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells

Includes abstract.

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Bibliographic Details
Main Author: Rose, Beverley Ann
Other Authors: Parker, Iqbal
Format: Thesis
Language:English
Published: Division of Medical Biochemistry 2015
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access_status_str Open Access
author Rose, Beverley Ann
author2 Parker, Iqbal
author_browse Parker, Iqbal
Rose, Beverley Ann
author_facet Parker, Iqbal
Rose, Beverley Ann
author_sort Rose, Beverley Ann
collection Thesis
description Includes abstract.
format Thesis
id oai:open.uct.ac.za:11427/10861
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:34:14.045Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2015
publishDateRange 2015
publishDateSort 2015
publisher Division of Medical Biochemistry
publisherStr Division of Medical Biochemistry
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/10861 The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells Rose, Beverley Ann Parker, Iqbal Leaner, Virna Medical Biochemistry Includes abstract. Includes bibliographical references (leaves 110-135). Recent studies have revealed that interactions between tumour cells and the surrounding stroma play an important role in facilitating tumour growth and invasion. Stromal fibroblasts produce most of the extracellular matrix (ECM) components found in the stroma, including type I collagen. Previous in vivo studies in our laboratory have shown that type I collagen mRNA levels are decreased in stage II and III breast tumour tissue compared to adjacent normal tissue. 2015-01-01T12:43:06Z 2015-01-01T12:43:06Z 2011 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/10861 eng application/pdf Division of Medical Biochemistry Faculty of Health Sciences University of Cape Town
spellingShingle Medical Biochemistry
Rose, Beverley Ann
The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
thesis_degree_str Doctoral
title The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
title_full The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
title_fullStr The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
title_full_unstemmed The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
title_short The regulation of type I collagen gene expression in stromal fibroblast by breast tumour cells
title_sort regulation of type i collagen gene expression in stromal fibroblast by breast tumour cells
topic Medical Biochemistry
url http://hdl.handle.net/11427/10861
work_keys_str_mv AT rosebeverleyann theregulationoftypeicollagengeneexpressioninstromalfibroblastbybreasttumourcells
AT rosebeverleyann regulationoftypeicollagengeneexpressioninstromalfibroblastbybreasttumourcells