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Determinants of innate immune responses to mycobacteria
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Paediatrics and Child Health
2015
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| _version_ | 1867614239245467648 |
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| access_status_str | Open Access |
| author | Shey, Muki Shehu |
| author2 | Hanekom, Willem A |
| author_browse | Hanekom, Willem A Shey, Muki Shehu |
| author_facet | Hanekom, Willem A Shey, Muki Shehu |
| author_sort | Shey, Muki Shehu |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/10986 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:48:52.923Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Paediatrics and Child Health |
| publisherStr | Department of Paediatrics and Child Health |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/10986 Determinants of innate immune responses to mycobacteria Shey, Muki Shehu Hanekom, Willem A Scriba, Thomas J Child and Adolescent Health Includes bibliographical references. Innate cells such as macrophages, monocytes, myeloid dendritic cells and granulocytes recognise mycobacteria and initiate immune responses such as phagocytosis, cytokine production and expression of maturation markers. The type and magnitude of innate responses to mycobacteria may determine the subsequent adaptive responses generated. Our aims were to determine maturational changes in innate immune responses to mycobacteria over the first 9 months of life, and to assess effects of genetic variations in toll-like receptors on host responses to mycobacteria. This knowledge is important for designing rational strategies for vaccination against tuberculosis. 2015-01-02T09:17:07Z 2015-01-02T09:17:07Z 2012 Doctoral Thesis Doctoral Ph D http://hdl.handle.net/11427/10986 eng application/pdf Department of Paediatrics and Child Health Faculty of Health Sciences University of Cape Town |
| spellingShingle | Child and Adolescent Health Shey, Muki Shehu Determinants of innate immune responses to mycobacteria |
| thesis_degree_str | Doctoral |
| title | Determinants of innate immune responses to mycobacteria |
| title_full | Determinants of innate immune responses to mycobacteria |
| title_fullStr | Determinants of innate immune responses to mycobacteria |
| title_full_unstemmed | Determinants of innate immune responses to mycobacteria |
| title_short | Determinants of innate immune responses to mycobacteria |
| title_sort | determinants of innate immune responses to mycobacteria |
| topic | Child and Adolescent Health |
| url | http://hdl.handle.net/11427/10986 |
| work_keys_str_mv | AT sheymukishehu determinantsofinnateimmuneresponsestomycobacteria |