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Computational rationale for the selective inhibition of the herpes simplex virus type 1 uracil-DNA glycosylase enzyme

In this thesis I will investigate the binding pocket and analyse the nature of binding of the 6-(4-Alkylanilino)-uracil inhibitors in hsvUDG and hUDG to provide a platform for the development of improved inhibitors.

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Bibliographic Details
Main Author: Hendricks, Umraan
Other Authors: Naidoo, Kevin J
Format: Thesis
Language:English
Published: Department of Chemistry 2015
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