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Early prediction of hypoxic ischaemic encephalopathy in newborn infants in a resource-limited setting
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Paediatrics and Child Health
2015
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| _version_ | 1867613714347196416 |
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| access_status_str | Open Access |
| author | Horn, Alan Richard |
| author2 | Swingler, George H |
| author_browse | Horn, Alan Richard Swingler, George H |
| author_facet | Swingler, George H Horn, Alan Richard |
| author_sort | Horn, Alan Richard |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/11188 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:40:32.341Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Paediatrics and Child Health |
| publisherStr | Department of Paediatrics and Child Health |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/11188 Early prediction of hypoxic ischaemic encephalopathy in newborn infants in a resource-limited setting Horn, Alan Richard Swingler, George H Myer, Landon Robertson, Nicola Paediatrics Includes bibliographical references. Hypoxic ischaemic encephalopathy (HIE) after birth is an important cause of neonatal morbidity and mortality, particularly in resource-limited regions. Therapeutic hypothermia initiated within the first 6 hours of life, in settings that can offer neonatal intensive care, is a therapy that can reduce death or severe disability in newborn infants with moderate or severe HIE. Therapeutic hypothermia has not been shown to be safe or effective in low-resource settings where neonatal intensive care is not available; however, there are situations such as in some centres in South Africa, where limited neonatal intensive care (NICU) is available against a background of moderate neonatal mortality rates, relatively low socio-economic conditions and limited capacity for long-term follow-up. In such settings, accurate case definition and early prediction of HIE and outcome may assist with the appropriate allocation of resources. The amplitude-integrated electro-encephalogram (aEEG) is an ideal tool to use for prediction of outcome and the need for cooling, but it’s availability is limited, particularly at primary and secondary hospitals. 2015-01-03T18:20:50Z 2015-01-03T18:20:50Z 2013 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/11188 eng application/pdf Department of Paediatrics and Child Health Faculty of Health Sciences University of Cape Town |
| spellingShingle | Paediatrics Horn, Alan Richard Early prediction of hypoxic ischaemic encephalopathy in newborn infants in a resource-limited setting |
| thesis_degree_str | Doctoral |
| title | Early prediction of hypoxic ischaemic encephalopathy in newborn infants in a resource-limited setting |
| title_full | Early prediction of hypoxic ischaemic encephalopathy in newborn infants in a resource-limited setting |
| title_fullStr | Early prediction of hypoxic ischaemic encephalopathy in newborn infants in a resource-limited setting |
| title_full_unstemmed | Early prediction of hypoxic ischaemic encephalopathy in newborn infants in a resource-limited setting |
| title_short | Early prediction of hypoxic ischaemic encephalopathy in newborn infants in a resource-limited setting |
| title_sort | early prediction of hypoxic ischaemic encephalopathy in newborn infants in a resource limited setting |
| topic | Paediatrics |
| url | http://hdl.handle.net/11427/11188 |
| work_keys_str_mv | AT hornalanrichard earlypredictionofhypoxicischaemicencephalopathyinnewborninfantsinaresourcelimitedsetting |