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HIV-associated sensory neuropathy in an African cohort a longitudinal study of risk factors predisposing to antiretroviral induced painful neuropathy
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Medicine
2015
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| _version_ | 1867614517170536448 |
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| access_status_str | Open Access |
| author | Van der Watt, Johan J |
| author2 | Heckmann, Jeannine M |
| author_browse | Heckmann, Jeannine M Van der Watt, Johan J |
| author_facet | Heckmann, Jeannine M Van der Watt, Johan J |
| author_sort | Van der Watt, Johan J |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/11621 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:53:17.970Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/11621 HIV-associated sensory neuropathy in an African cohort a longitudinal study of risk factors predisposing to antiretroviral induced painful neuropathy Van der Watt, Johan J Heckmann, Jeannine M Dandara, Collet Wilkinson, Robert J Includes abstract. Thesis (Ph.D. (Medicine))--University of Cape Town, 2013. Distal sensory polyneuropathy (DSP) amongst human immunodeficiency virus (HIV)-infected patients is frequently a painful and disabling condition. HIV-associated DSP is either a consequence of HIV (HIV-DSP) or antiretroviral-induced toxic neuropathy (ATN). The purpose of this research was to investigate the characteristics of HIV-associated DSP over the first 24 weeks of starting cART in an African community-based cohort. Apart from studying the longitudinal association of candidate risk factors based on previous reports, we focused on two additional aspects. Firstly, the Nacetyltransferase 2 (NAT2) genotype, which determines an individual's acetylation status, influences the risk for isoniazid (INH)-associated neuropathy. 2015-01-06T18:54:59Z 2015-01-06T18:54:59Z 2013 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/11621 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Van der Watt, Johan J HIV-associated sensory neuropathy in an African cohort a longitudinal study of risk factors predisposing to antiretroviral induced painful neuropathy |
| thesis_degree_str | Doctoral |
| title | HIV-associated sensory neuropathy in an African cohort a longitudinal study of risk factors predisposing to antiretroviral induced painful neuropathy |
| title_full | HIV-associated sensory neuropathy in an African cohort a longitudinal study of risk factors predisposing to antiretroviral induced painful neuropathy |
| title_fullStr | HIV-associated sensory neuropathy in an African cohort a longitudinal study of risk factors predisposing to antiretroviral induced painful neuropathy |
| title_full_unstemmed | HIV-associated sensory neuropathy in an African cohort a longitudinal study of risk factors predisposing to antiretroviral induced painful neuropathy |
| title_short | HIV-associated sensory neuropathy in an African cohort a longitudinal study of risk factors predisposing to antiretroviral induced painful neuropathy |
| title_sort | hiv associated sensory neuropathy in an african cohort a longitudinal study of risk factors predisposing to antiretroviral induced painful neuropathy |
| url | http://hdl.handle.net/11427/11621 |
| work_keys_str_mv | AT vanderwattjohanj hivassociatedsensoryneuropathyinanafricancohortalongitudinalstudyofriskfactorspredisposingtoantiretroviralinducedpainfulneuropathy |