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Acinetobacter baumannii : an evaluation of five susceptibility test methods to detect tobramycin resistance in an epidemiologically related cluster

Acinetobacter baumannii is a major pathogen causing nosocomial infections, particularly in critically ill patients. This organism has acquired the propensity to rapidly develop resistance to most antibiotics. At several hospitals within Cape Town, tobramycin and colistin remain frequently the only t...

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Main Author: Moodley, Vineshree Mischka
Other Authors: Oliver, Stephen
Format: Thesis
Language:English
Published: Division of Virology 2015
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access_status_str Open Access
author Moodley, Vineshree Mischka
author2 Oliver, Stephen
author_browse Moodley, Vineshree Mischka
Oliver, Stephen
author_facet Oliver, Stephen
Moodley, Vineshree Mischka
author_sort Moodley, Vineshree Mischka
collection Thesis
description Acinetobacter baumannii is a major pathogen causing nosocomial infections, particularly in critically ill patients. This organism has acquired the propensity to rapidly develop resistance to most antibiotics. At several hospitals within Cape Town, tobramycin and colistin remain frequently the only therapeutic options. The Vitek2 automated susceptibility testing (AST) is used in the clinical laboratory to determine selected susceptibility profiles. The suspicion of a possible AST-related technical error when testing for susceptibility to tobramycin in A. baumannii precipitated this study.
format Thesis
id oai:open.uct.ac.za:11427/11686
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:33:19.547Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2015
publishDateRange 2015
publishDateSort 2015
publisher Division of Virology
publisherStr Division of Virology
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/11686 Acinetobacter baumannii : an evaluation of five susceptibility test methods to detect tobramycin resistance in an epidemiologically related cluster Moodley, Vineshree Mischka Oliver, Stephen Elisha, B Gay Medical Virology Acinetobacter baumannii is a major pathogen causing nosocomial infections, particularly in critically ill patients. This organism has acquired the propensity to rapidly develop resistance to most antibiotics. At several hospitals within Cape Town, tobramycin and colistin remain frequently the only therapeutic options. The Vitek2 automated susceptibility testing (AST) is used in the clinical laboratory to determine selected susceptibility profiles. The suspicion of a possible AST-related technical error when testing for susceptibility to tobramycin in A. baumannii precipitated this study. 2015-01-07T13:29:07Z 2015-01-07T13:29:07Z 2011 Master Thesis Masters MMed http://hdl.handle.net/11427/11686 eng application/pdf Division of Virology Faculty of Health Sciences University of Cape Town
spellingShingle Medical Virology
Moodley, Vineshree Mischka
Acinetobacter baumannii : an evaluation of five susceptibility test methods to detect tobramycin resistance in an epidemiologically related cluster
thesis_degree_str Master's
title Acinetobacter baumannii : an evaluation of five susceptibility test methods to detect tobramycin resistance in an epidemiologically related cluster
title_full Acinetobacter baumannii : an evaluation of five susceptibility test methods to detect tobramycin resistance in an epidemiologically related cluster
title_fullStr Acinetobacter baumannii : an evaluation of five susceptibility test methods to detect tobramycin resistance in an epidemiologically related cluster
title_full_unstemmed Acinetobacter baumannii : an evaluation of five susceptibility test methods to detect tobramycin resistance in an epidemiologically related cluster
title_short Acinetobacter baumannii : an evaluation of five susceptibility test methods to detect tobramycin resistance in an epidemiologically related cluster
title_sort acinetobacter baumannii an evaluation of five susceptibility test methods to detect tobramycin resistance in an epidemiologically related cluster
topic Medical Virology
url http://hdl.handle.net/11427/11686
work_keys_str_mv AT moodleyvineshreemischka acinetobacterbaumanniianevaluationoffivesusceptibilitytestmethodstodetecttobramycinresistanceinanepidemiologicallyrelatedcluster