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The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of Immunology
2015
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| _version_ | 1867613177013862401 |
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| access_status_str | Open Access |
| author | Keeton, Roanne Shay |
| author2 | Jacobs, Muazzam |
| author_browse | Jacobs, Muazzam Keeton, Roanne Shay |
| author_facet | Jacobs, Muazzam Keeton, Roanne Shay |
| author_sort | Keeton, Roanne Shay |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/11889 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:58.458Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Division of Immunology |
| publisherStr | Division of Immunology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/11889 The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis Keeton, Roanne Shay Jacobs, Muazzam Immunology Includes abstract. Includes bibliographical references (leaves 85-97). Tumor necrosis factor alpha (TNFα) is critical for host protective immunity against Mycobacterium tuberculosis infection. TNFRp55 and TNFRp75 can both bind TNFα and conduct signaling, however the respective roles, in particular that of TNFRp75 in an M. tuberculosis aerosol inhalation infection was poorly defined. In this study the role of signaling through TNFRp55 and TNFRp75 was investigated using TNFR deficient mice in an aerosol inhalation M. tuberculosis infection model. 2015-01-10T06:47:52Z 2015-01-10T06:47:52Z 2009 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/11889 eng application/pdf Division of Immunology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Immunology Keeton, Roanne Shay The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis |
| thesis_degree_str | Doctoral |
| title | The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis |
| title_full | The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis |
| title_fullStr | The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis |
| title_full_unstemmed | The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis |
| title_short | The role of TNFRp55 and TNFRp75 in the host immune response to Mycobacterium tuberculosis |
| title_sort | role of tnfrp55 and tnfrp75 in the host immune response to mycobacterium tuberculosis |
| topic | Immunology |
| url | http://hdl.handle.net/11427/11889 |
| work_keys_str_mv | AT keetonroanneshay theroleoftnfrp55andtnfrp75inthehostimmuneresponsetomycobacteriumtuberculosis AT keetonroanneshay roleoftnfrp55andtnfrp75inthehostimmuneresponsetomycobacteriumtuberculosis |