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Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak.

Includes abstract.

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Bibliographic Details
Main Author: Modak, Ghabiba
Other Authors: Kellaway, Laurie A
Format: Thesis
Language:English
Published: Division of Biomedical Engineering 2015
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access_status_str Open Access
author Modak, Ghabiba
author2 Kellaway, Laurie A
author_browse Kellaway, Laurie A
Modak, Ghabiba
author_facet Kellaway, Laurie A
Modak, Ghabiba
author_sort Modak, Ghabiba
collection Thesis
description Includes abstract.
format Thesis
id oai:open.uct.ac.za:11427/11994
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:39:54.440Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2015
publishDateRange 2015
publishDateSort 2015
publisher Division of Biomedical Engineering
publisherStr Division of Biomedical Engineering
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/11994 Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak. Modak, Ghabiba Kellaway, Laurie A Sachs, NA Biomedical Engineering Includes abstract. Includes bibliographical references. Lower motor neuron damage often results in flaccid paralysis in which the affected muscles are unable to be stimulated artificially via the supplying nerve. Such damage is common in patients who suffer from spinal cord injury and Multiple Sclerosis. Current practice for artificial recovery of muscle function involves stimulating the muscles directly by means of Functional Electrical Stimulation (FES), which requires 100-1000 times more current than that required for nerve stimulation, thus presenting the risk of pain receptor activation. A potential alternative exists in chemical stimulation by means of administration of the neurotransmitter, Acetylcholine (ACh). This study investigates the potential of this possibility by examining the response of two muscle types to extracellular administration of ACh. 2015-01-10T13:35:20Z 2015-01-10T13:35:20Z 2011 Master Thesis Masters MSc http://hdl.handle.net/11427/11994 eng application/pdf Division of Biomedical Engineering Faculty of Health Sciences University of Cape Town
spellingShingle Biomedical Engineering
Modak, Ghabiba
Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak.
thesis_degree_str Master's
title Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak.
title_full Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak.
title_fullStr Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak.
title_full_unstemmed Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak.
title_short Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak.
title_sort characterisation of dynamics associated with skeletal muscle contraction initiated by acetylcholine injection ghabiba modak
topic Biomedical Engineering
url http://hdl.handle.net/11427/11994
work_keys_str_mv AT modakghabiba characterisationofdynamicsassociatedwithskeletalmusclecontractioninitiatedbyacetylcholineinjectionghabibamodak