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Includes abstract.
| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of Biomedical Engineering
2015
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| _version_ | 1867613674605117440 |
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| access_status_str | Open Access |
| author | Modak, Ghabiba |
| author2 | Kellaway, Laurie A |
| author_browse | Kellaway, Laurie A Modak, Ghabiba |
| author_facet | Kellaway, Laurie A Modak, Ghabiba |
| author_sort | Modak, Ghabiba |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/11994 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:39:54.440Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Division of Biomedical Engineering |
| publisherStr | Division of Biomedical Engineering |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/11994 Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak. Modak, Ghabiba Kellaway, Laurie A Sachs, NA Biomedical Engineering Includes abstract. Includes bibliographical references. Lower motor neuron damage often results in flaccid paralysis in which the affected muscles are unable to be stimulated artificially via the supplying nerve. Such damage is common in patients who suffer from spinal cord injury and Multiple Sclerosis. Current practice for artificial recovery of muscle function involves stimulating the muscles directly by means of Functional Electrical Stimulation (FES), which requires 100-1000 times more current than that required for nerve stimulation, thus presenting the risk of pain receptor activation. A potential alternative exists in chemical stimulation by means of administration of the neurotransmitter, Acetylcholine (ACh). This study investigates the potential of this possibility by examining the response of two muscle types to extracellular administration of ACh. 2015-01-10T13:35:20Z 2015-01-10T13:35:20Z 2011 Master Thesis Masters MSc http://hdl.handle.net/11427/11994 eng application/pdf Division of Biomedical Engineering Faculty of Health Sciences University of Cape Town |
| spellingShingle | Biomedical Engineering Modak, Ghabiba Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak. |
| thesis_degree_str | Master's |
| title | Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak. |
| title_full | Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak. |
| title_fullStr | Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak. |
| title_full_unstemmed | Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak. |
| title_short | Characterisation of dynamics associated with skeletal muscle contraction initiated by Acetylcholine injection Ghabiba Modak. |
| title_sort | characterisation of dynamics associated with skeletal muscle contraction initiated by acetylcholine injection ghabiba modak |
| topic | Biomedical Engineering |
| url | http://hdl.handle.net/11427/11994 |
| work_keys_str_mv | AT modakghabiba characterisationofdynamicsassociatedwithskeletalmusclecontractioninitiatedbyacetylcholineinjectionghabibamodak |