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Novel chemotherapeutic agents for oesophageal cancer
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of Medical Biochemistry
2015
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| _version_ | 1867613222227410945 |
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| access_status_str | Open Access |
| author | Khuzwayo, Londiwe Mandisa |
| author2 | Hendricks, Denver |
| author_browse | Hendricks, Denver Khuzwayo, Londiwe Mandisa |
| author_facet | Hendricks, Denver Khuzwayo, Londiwe Mandisa |
| author_sort | Khuzwayo, Londiwe Mandisa |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/12051 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:42.829Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Division of Medical Biochemistry |
| publisherStr | Division of Medical Biochemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/12051 Novel chemotherapeutic agents for oesophageal cancer Khuzwayo, Londiwe Mandisa Hendricks, Denver Medical Biochemistry Includes abstract. Includes bibliographical references. Chemotherapeutic agents such as cisplatin, doxorubicin and 5-fluorouracil are currently used in the treatment of a variety of cancers, including oesophageal cancer. Although these agents have been part of our therapeutic repertoire for many years, there are several side effects that have been associated with their use in cancer therapy. Thus there is a need to develop novel chemotherapeutic agents with improved activity and less severe side effects. In this project, twelve compounds, consisting of 5 platinum dichloride complexes, four iminophosphine ligands and three gold (I) chloride complexes that were synthesised by a PhD student in our laboratory were tested for anticancer activity and the mode of action of these compounds was also explored. 2015-01-11T04:57:39Z 2015-01-11T04:57:39Z 2012 Master Thesis Masters MSc http://hdl.handle.net/11427/12051 eng application/pdf Division of Medical Biochemistry Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medical Biochemistry Khuzwayo, Londiwe Mandisa Novel chemotherapeutic agents for oesophageal cancer |
| thesis_degree_str | Master's |
| title | Novel chemotherapeutic agents for oesophageal cancer |
| title_full | Novel chemotherapeutic agents for oesophageal cancer |
| title_fullStr | Novel chemotherapeutic agents for oesophageal cancer |
| title_full_unstemmed | Novel chemotherapeutic agents for oesophageal cancer |
| title_short | Novel chemotherapeutic agents for oesophageal cancer |
| title_sort | novel chemotherapeutic agents for oesophageal cancer |
| topic | Medical Biochemistry |
| url | http://hdl.handle.net/11427/12051 |
| work_keys_str_mv | AT khuzwayolondiwemandisa novelchemotherapeuticagentsforoesophagealcancer |