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Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials

Includes abstract.

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Bibliographic Details
Main Author: Nsumiwa, Samkele
Other Authors: Egan, Timothy J
Format: Thesis
Language:English
Published: Department of Chemistry 2015
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access_status_str Open Access
author Nsumiwa, Samkele
author2 Egan, Timothy J
author_browse Egan, Timothy J
Nsumiwa, Samkele
author_facet Egan, Timothy J
Nsumiwa, Samkele
author_sort Nsumiwa, Samkele
collection Thesis
description Includes abstract.
format Thesis
id oai:open.uct.ac.za:11427/12176
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:33:21.255Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2015
publishDateRange 2015
publishDateSort 2015
publisher Department of Chemistry
publisherStr Department of Chemistry
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/12176 Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials Nsumiwa, Samkele Egan, Timothy J Chibale, Kelly Chemistry Includes abstract. Includes bibliograhical references. The question of whether or not replacing the 7-chloro group in the 4-aminoquinoline moiety with an electron withdrawing and hydrophilic substituent results in retention of antiplasmodial activity in the 4-aminoquinoline class of compounds was investigated... 2015-01-14T07:21:09Z 2015-01-14T07:21:09Z 2010 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/12176 eng application/pdf Department of Chemistry Faculty of Science University of Cape Town
spellingShingle Chemistry
Nsumiwa, Samkele
Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials
thesis_degree_str Doctoral
title Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials
title_full Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials
title_fullStr Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials
title_full_unstemmed Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials
title_short Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials
title_sort synthesis and investigation of quinoline based ss haematin formation inhibitors as potential antimalarials
topic Chemistry
url http://hdl.handle.net/11427/12176
work_keys_str_mv AT nsumiwasamkele synthesisandinvestigationofquinolinebasedßhaematinformationinhibitorsaspotentialantimalarials