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Development of computational methods for custom protein arrays analysis : a case study on a 100-protein ("CT100") cancer/testis antigen array
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Molecular and Cell Biology
2015
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| _version_ | 1867613324641828864 |
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| access_status_str | Open Access |
| author | Safari Serufuri, Jean-Michel |
| author2 | Blackburn, Jonathan |
| author_browse | Blackburn, Jonathan Safari Serufuri, Jean-Michel |
| author_facet | Blackburn, Jonathan Safari Serufuri, Jean-Michel |
| author_sort | Safari Serufuri, Jean-Michel |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/12222 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:20.437Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Molecular and Cell Biology |
| publisherStr | Department of Molecular and Cell Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/12222 Development of computational methods for custom protein arrays analysis : a case study on a 100-protein ("CT100") cancer/testis antigen array Safari Serufuri, Jean-Michel Blackburn, Jonathan Mulder, Nicola Kumuthini, Judit Cell Biology Includes abstract. Includes bibliographical references (p. 49-52). Custom antigen arrays offer a platform to assay the serological response of cancer patients to at set of selected cancer testis antigens in order to infer a diagnosis value or to assess the patient responses to particular treatments. However, the acquisition of the array data is subject to bias and noise. Therefore, array data processing and analysis is required to clear the data from bias, reduce noise and learn from the data. This study aims to address the issues of normalization and sample qualitative clustering for custom protein arrays. 2015-01-15T11:28:24Z 2015-01-15T11:28:24Z 2010 Master Thesis Masters MSc http://hdl.handle.net/11427/12222 eng application/pdf Department of Molecular and Cell Biology Faculty of Science University of Cape Town |
| spellingShingle | Cell Biology Safari Serufuri, Jean-Michel Development of computational methods for custom protein arrays analysis : a case study on a 100-protein ("CT100") cancer/testis antigen array |
| thesis_degree_str | Master's |
| title | Development of computational methods for custom protein arrays analysis : a case study on a 100-protein ("CT100") cancer/testis antigen array |
| title_full | Development of computational methods for custom protein arrays analysis : a case study on a 100-protein ("CT100") cancer/testis antigen array |
| title_fullStr | Development of computational methods for custom protein arrays analysis : a case study on a 100-protein ("CT100") cancer/testis antigen array |
| title_full_unstemmed | Development of computational methods for custom protein arrays analysis : a case study on a 100-protein ("CT100") cancer/testis antigen array |
| title_short | Development of computational methods for custom protein arrays analysis : a case study on a 100-protein ("CT100") cancer/testis antigen array |
| title_sort | development of computational methods for custom protein arrays analysis a case study on a 100 protein ct100 cancer testis antigen array |
| topic | Cell Biology |
| url | http://hdl.handle.net/11427/12222 |
| work_keys_str_mv | AT safariserufurijeanmichel developmentofcomputationalmethodsforcustomproteinarraysanalysisacasestudyona100proteinct100cancertestisantigenarray |